APP - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
TAF9	TATA-box binding protein associated factor 9	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
TAF9B	TATA-box binding protein associated factor 9b	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Ub-specific processing proteases RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
TAFA4	TAFA chemokine like family member 4
TAGLN2	transgelin 2	Platelet degranulation	Artenimol
TANK	TRAF family member associated NFKB activator	TICAM1-dependent activation of IRF3/IRF7 TRAF6 mediated IRF7 activation Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation
TAP2	transporter 2, ATP binding cassette subfamily B member	ER-Phagosome pathway ER-Phagosome pathway Antigen Presentation: Folding, assembly and peptide loading of class I MHC		Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency Bare lymphocyte syndrome (BLS) type1
TARBP2	TARBP2 subunit of RISC loading complex	MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis PKR-mediated signaling
TARDBP	TAR DNA binding protein			Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
TASP1	taspase 1	Formation of WDR5-containing histone-modifying complexes Formation of WDR5-containing histone-modifying complexes
TBC1D10C	TBC1 domain family member 10C	Neutrophil degranulation TBC/RABGAPs
TBC1D20	TBC1 domain family member 20	COPII-mediated vesicle transport TBC/RABGAPs
TBC1D21	TBC1 domain family member 21
TBC1D26	TBC1 domain family member 26
TBC1D3P2	TBC1 domain family member 3 pseudogene 2
TBC1D7	TBC1 domain family member 7	TBC/RABGAPs
TBC1D9B	TBC1 domain family member 9B
TBCC	tubulin folding cofactor C	Post-chaperonin tubulin folding pathway
TBCD	tubulin folding cofactor D	Post-chaperonin tubulin folding pathway
TBCK	TBC1 domain containing kinase
TBK1	TANK binding kinase 1	IRF3 mediated activation of type 1 IFN IRF3 mediated activation of type 1 IFN DDX58/IFIH1-mediated induction of interferon-alpha/beta Regulation of innate immune responses to cytosolic DNA STAT6-mediated induction of chemokines IRF3-mediated induction of type I IFN PINK1-PRKN Mediated Mitophagy TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling Interleukin-37 signaling TICAM1-dependent activation of IRF3/IRF7 TRAF3-dependent IRF activation pathway TRAF6 mediated IRF7 activation Negative regulators of DDX58/IFIH1 signaling Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) Potential therapeutics for SARS SARS-CoV-1 activates/modulates innate immune responses SARS-CoV-2 activates/modulates innate and adaptive immune responses Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation	Fostamatinib

Search Results for: APP