PTEN - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	Nephrin family interactions
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3
MAP2K3	mitogen-activated protein kinase kinase 3	Oxidative Stress Induced Senescence activated TAK1 mediates p38 MAPK activation	Fostamatinib Pimasertib
MAST1	microtubule associated serine/threonine kinase 1		Fostamatinib
MAST2	microtubule associated serine/threonine kinase 2
MAST3	microtubule associated serine/threonine kinase 3
MATR3	matrin 3			Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
MCM2	minichromosome maintenance complex component 2	Activation of ATR in response to replication stress Unwinding of DNA Assembly of the pre-replicative complex Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex Switching of origins to a post-replicative state Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence
MCM3	minichromosome maintenance complex component 3	Activation of ATR in response to replication stress Unwinding of DNA Assembly of the pre-replicative complex Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex Switching of origins to a post-replicative state
MCM5	minichromosome maintenance complex component 5	Activation of ATR in response to replication stress Unwinding of DNA Assembly of the pre-replicative complex Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex Switching of origins to a post-replicative state Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence
MCRS1	microspherule protein 1	HATs acetylate histones UCH proteinases DNA Damage Recognition in GG-NER Formation of WDR5-containing histone-modifying complexes
MDC1	mediator of DNA damage checkpoint 1	SUMOylation of DNA damage response and repair proteins Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends TP53 Regulates Transcription of DNA Repair Genes G2/M DNA damage checkpoint
MDN1	midasin AAA ATPase 1
METTL26	methyltransferase like 26
MEX3C	mex-3 RNA binding family member C	Antigen processing: Ubiquitination & Proteasome degradation
MKI67	marker of proliferation Ki-67
MME	membrane metalloendopeptidase	Metabolism of Angiotensinogen to Angiotensins Physiological factors Neutrophil degranulation Developmental Lineage of Mammary Gland Myoepithelial Cells	Candoxatril Omapatrilat N-[3-[(1-Aminoethyl)(Hydroxy)Phosphoryl]-2-(1,1'-Biphenyl-4-Ylmethyl)Propanoyl]Alanine Phosphoramidon N-(3-Phenyl-2-Sulfanylpropanoyl)Phenylalanylalanine [2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala Daglutril 2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM Thiorphan Sacubitril Candoxatrilat
MPRIP	myosin phosphatase Rho interacting protein	Signaling by BRAF and RAF1 fusions
MRPS22	mitochondrial ribosomal protein S22	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control		Combined oxidative phosphorylation deficiency (COXPD)
MRPS23	mitochondrial ribosomal protein S23	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control

Search Results for: PTEN