Search Results for: CDKN2A

173 interactions involving CDKN2A - cyclin dependent kinase inhibitor 2A found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
UBL7 ubiquitin like 7
USP26 ubiquitin specific peptidase 26
  • Ub-specific processing proteases
VAMP1 vesicle associated membrane protein 1
  • Toxicity of botulinum toxin type D (botD)
  • Toxicity of botulinum toxin type F (botF)
  • Toxicity of botulinum toxin type G (botG)
  • Botulinum toxin type B
VHL von Hippel-Lindau tumor suppressor
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • SUMOylation of ubiquitinylation proteins
  • Neddylation
  • Replication of the SARS-CoV-1 genome
  • Replication of the SARS-CoV-2 genome
  • RHOBTB3 ATPase cycle
  • Antigen processing: Ubiquitination & Proteasome degradation
  • von Hippel-Lindau syndrome
  • Congenital polycythemia; Familial erythrocytosis (ECYT)
  • Renal cell carcinoma
WRN WRN RecQ like helicase
  • Processive synthesis on the C-strand of the telomere
  • Removal of the Flap Intermediate from the C-strand
  • SUMOylation of DNA damage response and repair proteins
  • HDR through Single Strand Annealing (SSA)
  • HDR through Homologous Recombination (HRR)
  • Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
  • Resolution of D-loop Structures through Holliday Junction Intermediates
  • Homologous DNA Pairing and Strand Exchange
  • Processing of DNA double-strand break ends
  • Presynaptic phase of homologous DNA pairing and strand exchange
  • Regulation of TP53 Activity through Phosphorylation
  • G2/M DNA damage checkpoint
  • Defective homologous recombination repair (HRR) due to BRCA1 loss of function
  • Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function
  • Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
  • Impaired BRCA2 binding to RAD51
  • Impaired BRCA2 binding to PALB2
  • Defects in RecQ helicases, including: Bloom's syndrome; Werner's syndrome; Rothmund-Thomson syndrome
YY1 YY1 transcription factor
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • UCH proteinases
  • DNA Damage Recognition in GG-NER
  • TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
  • Estrogen-dependent gene expression
ZFP91 ZFP91 zinc finger protein, atypical E3 ubiquitin ligase
ZGRF1 zinc finger GRF-type containing 1
ZNF227 zinc finger protein 227
  • Generic Transcription Pathway
ZNF410 zinc finger protein 410
ZNF420 zinc finger protein 420
  • Generic Transcription Pathway
  • TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
ZNF687 zinc finger protein 687
ZUP1 zinc finger containing ubiquitin peptidase 1

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