APP - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
STARD10	StAR related lipid transfer domain containing 10	Synthesis of PC
STAT5B	signal transducer and activator of transcription 5B	Prolactin receptor signaling Interleukin-7 signaling Interleukin-7 signaling Signaling by SCF-KIT Signaling by cytosolic FGFR1 fusion mutants Downstream signal transduction Signaling by Leptin Interleukin-3, Interleukin-5 and GM-CSF signaling Interleukin-3, Interleukin-5 and GM-CSF signaling Interleukin-20 family signaling Interleukin-15 signaling Interleukin-9 signaling Interleukin-2 signaling Interleukin-2 signaling Interleukin-21 signaling Erythropoietin activates STAT5 STAT5 Activation Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants Signaling by CSF3 (G-CSF) STAT5 activation downstream of FLT3 ITD mutants Signaling by FLT3 fusion proteins Inactivation of CSF3 (G-CSF) signaling Growth hormone receptor signaling Growth hormone receptor signaling	Dasatinib	Growth hormone insensitivity with immunodeficiency
STAU1	staufen double-stranded RNA binding protein 1
STEEP1	STING1 ER exit protein 1	mRNA Splicing - Major Pathway
STIP1	stress induced phosphoprotein 1	HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand RND1 GTPase cycle	Copper
STK11	serine/threonine kinase 11	AMPK inhibits chREBP transcriptional activation activity Energy dependent regulation of mTOR by LKB1-AMPK Regulation of TP53 Activity through Phosphorylation FOXO-mediated transcription of cell death genes		Peutz-Jeghers syndrome Pancreatic cancer
STK17B	serine/threonine kinase 17b		Quercetin Fostamatinib
STK25	serine/threonine kinase 25
STK26	serine/threonine kinase 26	Apoptotic cleavage of cellular proteins	2-[4-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]iminocyclohexa-2,5-dien-1-yl]acetonitrile Fostamatinib
STK33	serine/threonine kinase 33		Fostamatinib
STK40	serine/threonine kinase 40
STN1	STN1 subunit of CST complex	Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation
STOML1	stomatin like 1
STOML2	stomatin like 2	Processing of SMDT1 Cellular response to mitochondrial stress
STOML3	stomatin like 3	Stimuli-sensing channels
STRIP2	striatin interacting protein 2
STX11	syntaxin 11			Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
STXBP1	syntaxin binding protein 1	Regulation of insulin secretion Neurexins and neuroligins		Early infantile epileptic encephalopathy; Ohtahara syndrome
SUB1	SUB1 regulator of transcription
SULF1	sulfatase 1

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