APP - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
SMYD3	SET and MYND domain containing 3	PKMTs methylate histone lysines
SNAI2	snail family transcriptional repressor 2	Regulation of PTEN gene transcription Regulation of PTEN gene transcription Negative Regulation of CDH1 Gene Transcription Transcriptional and post-translational regulation of MITF-M expression and activity		Waardenburg syndrome (WS) Piebaldism
SNAP25	synaptosome associated protein 25	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Regulation of insulin secretion Other interleukin signaling Toxicity of botulinum toxin type A (botA) Toxicity of botulinum toxin type C (botC) Toxicity of botulinum toxin type E (botE) Neutrophil degranulation GABA synthesis, release, reuptake and degradation Sensory processing of sound by inner hair cells of the cochlea	Botulinum toxin type A Letibotulinumtoxina
SNCA	synuclein alpha	Amyloid fiber formation PKR-mediated signaling	Resveratrol Dequalinium Copper	Lewy body dementia (LBD); Dementia with Lewy bodies (DLB) Parkinson's disease (PD)
SNCB	synuclein beta	MTF1 activates gene expression		Lewy body dementia (LBD); Dementia with Lewy bodies (DLB)
SND1	staphylococcal nuclease and tudor domain containing 1	Signaling by BRAF and RAF1 fusions
SNRNP35	small nuclear ribonucleoprotein U11/U12 subunit 35	mRNA Splicing - Minor Pathway
SNRNP40	small nuclear ribonucleoprotein U5 subunit 40	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
SNRNP70	small nuclear ribonucleoprotein U1 subunit 70	mRNA Splicing - Major Pathway
SNURF	SNRPN upstream open reading frame
SNX1	sorting nexin 1
SNX17	sorting nexin 17
SNX21	sorting nexin family member 21
SNX27	sorting nexin 27
SOCS3	suppressor of cytokine signaling 3	Interleukin-6 signaling Signaling by Leptin Interleukin-4 and Interleukin-13 signaling Interferon gamma signaling Regulation of IFNG signaling PTK6 Activates STAT3 RUNX1 regulates transcription of genes involved in differentiation of keratinocytes Neddylation Interferon alpha/beta signaling Regulation of IFNA/IFNB signaling Signaling by CSF3 (G-CSF) Inactivation of CSF3 (G-CSF) signaling Inactivation of CSF3 (G-CSF) signaling Growth hormone receptor signaling Antigen processing: Ubiquitination & Proteasome degradation
SOCS5	suppressor of cytokine signaling 5	Interleukin-4 and Interleukin-13 signaling Neddylation
SOD2	superoxide dismutase 2	Transcriptional activation of mitochondrial biogenesis Detoxification of Reactive Oxygen Species Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes Mitochondrial unfolded protein response (UPRmt)	Benzylsulfonic acid 3-Fluoro-L-tyrosine Benzoyl peroxide
SOX5	SRY-box transcription factor 5
SOX7	SRY-box transcription factor 7	Deactivation of the beta-catenin transactivating complex
SP140L	SP140 nuclear body protein like

Search Results for: APP