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TLR2 |
toll like receptor 2 |
- ER-Phagosome pathway
- Beta defensins
- MyD88:MAL(TIRAP) cascade initiated on plasma membrane
- Toll Like Receptor TLR1:TLR2 Cascade
- Toll Like Receptor TLR6:TLR2 Cascade
- MyD88 deficiency (TLR2/4)
- IRAK4 deficiency (TLR2/4)
- Regulation of TLR by endogenous ligand
- Neutrophil degranulation
- Modulation by Mtb of host immune system
- SARS-CoV-2 activates/modulates innate and adaptive immune responses
- RSV-host interactions
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- Lyme disease vaccine (recombinant OspA)
- Adapalene
- S-(Dimethylarsenic)Cysteine
- Golotimod
- Tuberculin purified protein derivative
- Pam2csk4
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TLR6 |
toll like receptor 6 |
- ER-Phagosome pathway
- MyD88:MAL(TIRAP) cascade initiated on plasma membrane
- Toll Like Receptor TLR6:TLR2 Cascade
- MyD88 deficiency (TLR2/4)
- IRAK4 deficiency (TLR2/4)
- Regulation of TLR by endogenous ligand
- RSV-host interactions
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TLR9 |
toll like receptor 9 |
- PI3K Cascade
- Trafficking and processing of endosomal TLR
- Toll Like Receptor 9 (TLR9) Cascade
- Potential therapeutics for SARS
- TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
- MyD88 dependent cascade initiated on endosome
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- Chloroquine
- Hydroxychloroquine
- ISS-1018
- Golotimod
- CPG 10101
- Tilsotolimod
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TP73 |
tumor protein p73 |
- Activation of PUMA and translocation to mitochondria
- TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
- TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
- TP53 Regulates Transcription of Caspase Activators and Caspases
- TP53 Regulates Transcription of Death Receptors and Ligands
- Regulation of TP53 Activity through Association with Co-factors
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
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- Zinc
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
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TTC1 |
tetratricopeptide repeat domain 1 |
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TTC21A |
tetratricopeptide repeat domain 21A |
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TTC28 |
tetratricopeptide repeat domain 28 |
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UBE3B |
ubiquitin protein ligase E3B |
- Antigen processing: Ubiquitination & Proteasome degradation
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UBE4B |
ubiquitination factor E4B |
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USP29 |
ubiquitin specific peptidase 29 |
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USP42 |
ubiquitin specific peptidase 42 |
- Ub-specific processing proteases
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VAV1 |
vav guanine nucleotide exchange factor 1 |
- GPVI-mediated activation cascade
- GPVI-mediated activation cascade
- PIP3 activates AKT signaling
- Signaling by SCF-KIT
- NRAGE signals death through JNK
- Regulation of actin dynamics for phagocytic cup formation
- Constitutive Signaling by Aberrant PI3K in Cancer
- FCERI mediated MAPK activation
- FCERI mediated Ca+2 mobilization
- FCERI mediated Ca+2 mobilization
- CD28 dependent Vav1 pathway
- G alpha (12/13) signalling events
- VEGFA-VEGFR2 Pathway
- VEGFA-VEGFR2 Pathway
- Interleukin-3, Interleukin-5 and GM-CSF signaling
- VEGFR2 mediated vascular permeability
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
- RHOA GTPase cycle
- RAC1 GTPase cycle
- RAC2 GTPase cycle
- RHOG GTPase cycle
- Erythropoietin activates RAS
- Erythropoietin activates RAS
- Regulation of signaling by CBL
- FCGR3A-mediated phagocytosis
- FCGR3A-mediated phagocytosis
- Potential therapeutics for SARS
- Azathioprine ADME
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
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ZBTB10 |
zinc finger and BTB domain containing 10 |
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ZBTB12 |
zinc finger and BTB domain containing 12 |
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ZDHHC9 |
zDHHC palmitoyltransferase 9 |
- RAS processing
- Maturation of spike protein
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- Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
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