Search Results for: APP

2116 interactions involving APP - amyloid beta precursor protein found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
RIOK2 RIO kinase 2
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Fostamatinib
RIOX2 ribosomal oxygenase 2
  • HDMs demethylate histones
  • Protein hydroxylation
RIT2 Ras like without CAAX 2
  • Signalling to p38 via RIT and RIN
RITA1 RBPJ interacting and tubulin associated 1
RLBP1 retinaldehyde binding protein 1
  • The retinoid cycle in cones (daylight vision)
  • The retinoid cycle in cones (daylight vision)
  • The canonical retinoid cycle in rods (twilight vision)
  • Defective visual phototransduction due to RDH5 loss of function
  • Newfoundland rod-cone dystrophy (NFRCD)
  • Familial flecked retina syndrome, including: Doyne honeycomb degeneration of retina (DHRD); Basal laminar drusen (BLD); Fundus albipunctatus (FA); Retinitis punctata albescens (RPA); Bietti crystalline corneoretinal dystrophy (BCD)
RMND5A required for meiotic nuclear division 5 homolog A
  • Regulation of pyruvate metabolism
RMP24 ribonuclease MRP subunit p24
RNASE11 ribonuclease A family member 11 (inactive)
RNF11 ring finger protein 11
RNF115 ring finger protein 115
  • Antigen processing: Ubiquitination & Proteasome degradation
RNF123 ring finger protein 123
  • Ub-specific processing proteases
  • Antigen processing: Ubiquitination & Proteasome degradation
RNF138 ring finger protein 138
  • Antigen processing: Ubiquitination & Proteasome degradation
RNF151 ring finger protein 151
RNF183 ring finger protein 183
RNF185 ring finger protein 185
  • ABC-family proteins mediated transport
  • Defective CFTR causes cystic fibrosis
  • ER Quality Control Compartment (ERQC)
  • AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
RNF32 ring finger protein 32
RNF34 ring finger protein 34
  • Regulation of TP53 Degradation
  • Antigen processing: Ubiquitination & Proteasome degradation
RNF41 ring finger protein 41
  • Downregulation of ERBB2:ERBB3 signaling
  • Antigen processing: Ubiquitination & Proteasome degradation
RNPC3 RNA binding region (RNP1, RRM) containing 3
  • mRNA Splicing - Minor Pathway
ROBO3 roundabout guidance receptor 3

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