Search Results for: APP

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
RAPGEFL1 Rap guanine nucleotide exchange factor like 1
RASA1 RAS p21 protein activator 1
  • Downstream signal transduction
  • EPHB-mediated forward signaling
  • EPHB-mediated forward signaling
  • VEGFR2 mediated cell proliferation
  • Regulation of RAS by GAPs
  • PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
  • RASA1-related disorders, including: Parkes-Weber slndrome; Capillary malformation-arteriovenous malformation (CM-AVM); Arteriovenous fistula (AVF)
RASA3 RAS p21 protein activator 3
  • Regulation of RAS by GAPs
RASGRP2 RAS guanyl releasing protein 2
  • Effects of PIP2 hydrolysis
  • FCERI mediated NF-kB activation
  • Integrin signaling
  • Rap1 signalling
RASGRP3 RAS guanyl releasing protein 3
  • Activation of RAS in B cells
  • Activation of RAS in B cells
  • RAF/MAP kinase cascade
RASL10B RAS like family 10 member B
RASL11B RAS like family 11 member B
RASL12 RAS like family 12
RASSF3 Ras association domain family member 3
RASSF8 Ras association domain family member 8
RBCK1 RANBP2-type and C3HC4-type zinc finger containing 1
  • TNFR1-induced proapoptotic signaling
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • Antigen processing: Ubiquitination & Proteasome degradation
RBM11 RNA binding motif protein 11
RBM34 RNA binding motif protein 34
RBM39 RNA binding motif protein 39
  • mRNA Splicing - Major Pathway
RBM42 RNA binding motif protein 42
  • mRNA Splicing - Major Pathway
RBM4B RNA binding motif protein 4B
RBM8A RNA binding motif protein 8A
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
  • mRNA Splicing - Major Pathway
  • mRNA 3'-end processing
  • RNA Polymerase II Transcription Termination
  • Regulation of expression of SLITs and ROBOs
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
RBPJ recombination signal binding protein for immunoglobulin kappa J region
  • Pre-NOTCH Transcription and Translation
  • Pre-NOTCH Transcription and Translation
  • Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
  • NOTCH1 Intracellular Domain Regulates Transcription
  • NOTCH1 Intracellular Domain Regulates Transcription
  • NOTCH2 intracellular domain regulates transcription
  • NOTCH2 intracellular domain regulates transcription
  • Constitutive Signaling by NOTCH1 PEST Domain Mutants
  • Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
  • Notch-HLH transcription pathway
  • RUNX3 regulates NOTCH signaling
  • RUNX3 regulates NOTCH signaling
  • NOTCH3 Intracellular Domain Regulates Transcription
  • NOTCH3 Intracellular Domain Regulates Transcription
  • NOTCH4 Intracellular Domain Regulates Transcription
  • NOTCH4 Intracellular Domain Regulates Transcription
  • Formation of paraxial mesoderm
  • Somitogenesis
RBPJL recombination signal binding protein for immunoglobulin kappa J region like
RBX1 ring-box 1
  • Recognition of DNA damage by PCNA-containing replication complex
  • Prolactin receptor signaling
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • Vif-mediated degradation of APOBEC3G
  • Degradation of beta-catenin by the destruction complex
  • NOTCH1 Intracellular Domain Regulates Transcription
  • Constitutive Signaling by NOTCH1 PEST Domain Mutants
  • Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling
  • Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
  • Degradation of DVL
  • Degradation of GLI1 by the proteasome
  • Degradation of GLI2 by the proteasome
  • GLI3 is processed to GLI3R by the proteasome
  • Hedgehog 'on' state
  • Regulation of RAS by GAPs
  • DNA Damage Recognition in GG-NER
  • Formation of Incision Complex in GG-NER
  • Dual Incision in GG-NER
  • Formation of TC-NER Pre-Incision Complex
  • Transcription-Coupled Nucleotide Excision Repair (TC-NER)
  • Dual incision in TC-NER
  • Gap-filling DNA repair synthesis and ligation in TC-NER
  • Orc1 removal from chromatin
  • Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A
  • FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
  • Regulation of RUNX2 expression and activity
  • Neddylation
  • Regulation of expression of SLITs and ROBOs
  • Interleukin-1 signaling
  • Negative regulation of NOTCH4 signaling
  • Potential therapeutics for SARS
  • Regulation of BACH1 activity
  • Nuclear events stimulated by ALK signaling in cancer
  • KEAP1-NFE2L2 pathway
  • GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2
  • Antigen processing: Ubiquitination & Proteasome degradation
  • Evasion by RSV of host interferon responses
  • GSK3B-mediated proteasomal degradation of PD-L1(CD274)
  • SPOP-mediated proteasomal degradation of PD-L1(CD274)
  • Degradation of CRY and PER proteins
  • Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide

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