|
|
BHLHE40 |
basic helix-loop-helix family member e40 |
- BMAL1:CLOCK,NPAS2 activates circadian expression
- Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes
|
|
|
|
|
BLZF1 |
basic leucine zipper nuclear factor 1 |
- Golgi Cisternae Pericentriolar Stack Reorganization
|
|
|
|
|
CALR |
calreticulin |
- ER-Phagosome pathway
- Assembly of Viral Components at the Budding Site
- Scavenging by Class A Receptors
- Scavenging by Class A Receptors
- Scavenging by Class F Receptors
- Scavenging by Class F Receptors
- ATF6 (ATF6-alpha) activates chaperone genes
- Calnexin/calreticulin cycle
- Antigen Presentation: Folding, assembly and peptide loading of class I MHC
|
- Antihemophilic factor, human recombinant
- Tenecteplase
- Melatonin
- Lanoteplase
- Copper
- Calcium citrate
- Calcium Phosphate
- Lonoctocog alfa
- Moroctocog alfa
- Calcium phosphate dihydrate
|
|
|
|
CAMK2D |
calcium/calmodulin dependent protein kinase II delta |
- CaMK IV-mediated phosphorylation of CREB
- HSF1-dependent transactivation
- Trafficking of AMPA receptors
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Ras activation upon Ca2+ influx through NMDA receptor
- Phase 0 - rapid depolarisation
- Ion homeostasis
- RAF activation
- RAF/MAP kinase cascade
- Signaling by moderate kinase activity BRAF mutants
- Signaling by BRAF and RAF1 fusions
- Paradoxical activation of RAF signaling by kinase inactive BRAF
- Interferon gamma signaling
- Regulation of MECP2 expression and activity
- Ion transport by P-type ATPases
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
- Signaling downstream of RAS mutants
- Signaling by RAF1 mutants
|
- 2-[4-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]iminocyclohexa-2,5-dien-1-yl]acetonitrile
- (3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE
- Fostamatinib
|
|
|
|
CCDC120 |
coiled-coil domain containing 120 |
|
|
|
|
|
CCDC33 |
coiled-coil domain containing 33 |
|
|
|
|
|
CD69 |
CD69 molecule |
|
|
|
|
|
CDC23 |
cell division cycle 23 |
- Inactivation of APC/C via direct inhibition of the APC/C complex
- APC/C:Cdc20 mediated degradation of Cyclin B
- Autodegradation of Cdh1 by Cdh1:APC/C
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
- Regulation of APC/C activators between G1/S and early anaphase
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Phosphorylation of the APC/C
- APC-Cdc20 mediated degradation of Nek2A
- Separation of Sister Chromatids
- Senescence-Associated Secretory Phenotype (SASP)
- Assembly of the pre-replicative complex
- CDK-mediated phosphorylation and removal of Cdc6
- Transcriptional Regulation by VENTX
- Aberrant regulation of mitotic exit in cancer due to RB1 defects
- Antigen processing: Ubiquitination & Proteasome degradation
|
|
|
|
|
CDX2 |
caudal type homeobox 2 |
- Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
|
|
|
|
|
CEBPB |
CCAAT enhancer binding protein beta |
- Senescence-Associated Secretory Phenotype (SASP)
- Senescence-Associated Secretory Phenotype (SASP)
- ATF4 activates genes in response to endoplasmic reticulum stress
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional Regulation by VENTX
- Transcriptional regulation of granulopoiesis
- Response of EIF2AK4 (GCN2) to amino acid deficiency
- Response of EIF2AK4 (GCN2) to amino acid deficiency
- Response of EIF2AK1 (HRI) to heme deficiency
- Response of EIF2AK1 (HRI) to heme deficiency
- Nuclear events stimulated by ALK signaling in cancer
|
|
|
|
|
CHFR |
checkpoint with forkhead and ring finger domains |
|
|
|
|
|
CNTNAP3 |
contactin associated protein family member 3 |
|
|
|
|
|
CXCL11 |
C-X-C motif chemokine ligand 11 |
- Chemokine receptors bind chemokines
- G alpha (i) signalling events
|
|
|
|
|
CYB5D2 |
cytochrome b5 domain containing 2 |
|
|
|
|
|
DNAJA3 |
DnaJ heat shock protein family (Hsp40) member A3 |
|
|
|
|
|
DPH6 |
diphthamine biosynthesis 6 |
- Synthesis of diphthamide-EEF2
|
|
|
|
|
EZH2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
- PRC2 methylates histones and DNA
- Oxidative Stress Induced Senescence
- PKMTs methylate histone lysines
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- Regulation of PTEN gene transcription
- Regulation of PTEN gene transcription
- Transcriptional Regulation by E2F6
- HCMV Early Events
- Defective pyroptosis
- Negative Regulation of CDH1 Gene Transcription
- Regulation of PD-L1(CD274) transcription
|
|
|
|
|
FAM90A1 |
family with sequence similarity 90 member A1 |
|
|
|
|
|
FAM9B |
family with sequence similarity 9 member B |
|
|
|
|
|
FUS |
FUS RNA binding protein |
- mRNA Splicing - Major Pathway
- Processing of Capped Intron-Containing Pre-mRNA
|
|
- Myxoid liposarcoma
- Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
|