Search Results for: APP

2116 interactions involving APP - amyloid beta precursor protein found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  • ISG15 antiviral mechanism
  • RHO GTPases Activate NADPH Oxidases
  • Regulation of TP53 Activity through Phosphorylation
  • PI5P Regulates TP53 Acetylation
  • Negative regulators of DDX58/IFIH1 signaling
  • Beta-(2-Naphthyl)-Alanine
  • 3,6,9,12,15,18-HEXAOXAICOSANE
PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
  • Synthesis of PIPs at the plasma membrane
  • PI5P Regulates TP53 Acetylation
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • Synthesis of PIPs in the nucleus
  • Fostamatinib
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
  • Synthesis of PIPs at the plasma membrane
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
PKM pyruvate kinase M1/2
  • Neutrophil degranulation
  • Negative Regulation of CDH1 Gene Transcription
  • Pyruvic acid
  • L-Phospholactate
  • 2-Phosphoglycolic Acid
  • 6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one
  • 1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine
  • 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine
  • Indoprofen
  • Copper
  • Polydatin
  • Artenimol
PKNOX1 PBX/knotted 1 homeobox 1
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
PLA1A phospholipase A1 member A
  • Acyl chain remodelling of PS
PLA2G4C phospholipase A2 group IVC
  • Acyl chain remodelling of PC
  • Acyl chain remodelling of PE
  • Acyl chain remodelling of PI
  • Hydrolysis of LPC
  • Hydrolysis of LPE
PLA2G4D phospholipase A2 group IVD
  • Acyl chain remodelling of PC
  • Acyl chain remodelling of PS
  • Acyl chain remodelling of PE
  • Acyl chain remodelling of PI
  • Acyl chain remodelling of PG
  • Hydrolysis of LPC
  • Synthesis of PA
PLAAT1 phospholipase A and acyltransferase 1
  • Acyl chain remodelling of PE
PLAAT5 phospholipase A and acyltransferase 5
  • Acyl chain remodelling of PE
PLAT plasminogen activator, tissue type
  • Signaling by PDGF
  • Dissolution of Fibrin Clot
  • Aminocaproic acid
  • Iloprost
  • Human C1-esterase inhibitor
  • 5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID
  • Dexibuprofen
  • Conestat alfa
PLBD1 phospholipase B domain containing 1
  • Acyl chain remodelling of PC
  • Acyl chain remodelling of PE
  • Acyl chain remodelling of PI
  • Hydrolysis of LPC
PLCD1 phospholipase C delta 1
  • Synthesis of IP3 and IP4 in the cytosol
  • 1D-myo-inositol 1,4,5-trisphosphate
  • Inositol 2,4,5-trisphosphate
PLCD4 phospholipase C delta 4
  • Synthesis of IP3 and IP4 in the cytosol
PLEKHF2 pleckstrin homology and FYVE domain containing 2
PLEKHG2 pleckstrin homology and RhoGEF domain containing G2
  • NRAGE signals death through JNK
  • G alpha (12/13) signalling events
  • CDC42 GTPase cycle
  • RAC1 GTPase cycle
PLEKHJ1 pleckstrin homology domain containing J1
PLEKHO2 pleckstrin homology domain containing O2
  • Neutrophil degranulation
PLIN3 perilipin 3
  • Triglyceride catabolism
  • Retrograde transport at the Trans-Golgi-Network
  • Lipophagy
  • Chaperone Mediated Autophagy
  • Late endosomal microautophagy
  • RHOBTB3 ATPase cycle
  • Idursulfase
  • Galsulfase

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