Search Results for: APP

2116 interactions involving APP - amyloid beta precursor protein found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
OLFML2A olfactomedin like 2A
OPA1 OPA1 mitochondrial dynamin like GTPase
  • Regulation of Apoptosis
  • Mitochondrial protein degradation
  • Autosomal dominant optic atrophy (DOA); Kjer's optic neuropathy
  • Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
OPA3 outer mitochondrial membrane lipid metabolism regulator OPA3
  • Autosomal dominant optic atrophy (DOA); Kjer's optic neuropathy
  • 3-Methylglutaconic aciduria (MGCA)
OR2W1 olfactory receptor family 2 subfamily W member 1
  • Olfactory Signaling Pathway
  • Olfactory Signaling Pathway
  • Expression and translocation of olfactory receptors
OR4D6 olfactory receptor family 4 subfamily D member 6
  • Expression and translocation of olfactory receptors
OR6B3 olfactory receptor family 6 subfamily B member 3
  • Expression and translocation of olfactory receptors
OR7A5 olfactory receptor family 7 subfamily A member 5
  • Expression and translocation of olfactory receptors
ORC3 origin recognition complex subunit 3
  • E2F-enabled inhibition of pre-replication complex formation
  • Activation of ATR in response to replication stress
  • Assembly of the ORC complex at the origin of replication
  • CDC6 association with the ORC:origin complex
  • Assembly of the pre-replicative complex
  • Orc1 removal from chromatin
  • Activation of the pre-replicative complex
ORC4 origin recognition complex subunit 4
  • E2F-enabled inhibition of pre-replication complex formation
  • Activation of ATR in response to replication stress
  • Assembly of the ORC complex at the origin of replication
  • CDC6 association with the ORC:origin complex
  • Assembly of the pre-replicative complex
  • Orc1 removal from chromatin
  • Activation of the pre-replicative complex
  • Patella dysplasias, including: Small patella syndrome (SPS); Nail-patella syndrome; Ear-patella-short statute syndrome
ORC6 origin recognition complex subunit 6
  • E2F-enabled inhibition of pre-replication complex formation
  • Activation of ATR in response to replication stress
  • Assembly of the ORC complex at the origin of replication
  • CDC6 association with the ORC:origin complex
  • Assembly of the pre-replicative complex
  • Orc1 removal from chromatin
  • Activation of the pre-replicative complex
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1
  • Sphingolipid de novo biosynthesis
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
  • Sphingolipid de novo biosynthesis
  • Neutrophil degranulation
OSBPL11 oxysterol binding protein like 11
  • RHOH GTPase cycle
OSBPL5 oxysterol binding protein like 5
  • Acyl chain remodelling of PS
OSM oncostatin M
  • Interleukin-4 and Interleukin-13 signaling
  • IL-6-type cytokine receptor ligand interactions
OSTCP1 oligosaccharyltransferase complex subunit pseudogene 1
OSTF1 osteoclast stimulating factor 1
  • Neutrophil degranulation
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
  • Ovarian tumor domain proteases
OTX2 orthodenticle homeobox 2
  • Formation of the anterior neural plate
  • Formation of the posterior neural plate
  • Anophthalmia and microphthalmia (A/M)
  • Septo-optic dysplasia
OXSM 3-oxoacyl-ACP synthase, mitochondrial
  • Mitochondrial protein degradation

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