APP - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide
NUDT9	nudix hydrolase 9		Beta-D-Glucose beta-D-Ribose-5-phosphate
NUMB	NUMB endocytic adaptor protein	Activated NOTCH1 Transmits Signal to the Nucleus Recycling pathway of L1 Degradation of GLI1 by the proteasome Hedgehog 'on' state Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
NUMBL	NUMB like endocytic adaptor protein
NUP50	nucleoporin 50	ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events SARS-CoV-2 activates/modulates innate and adaptive immune responses
NUP62CL	nucleoporin 62 C-terminal like
NUSAP1	nucleolar and spindle associated protein 1
NXF2	nuclear RNA export factor 2	Transport of Mature mRNA derived from an Intron-Containing Transcript
NXPE3	neurexophilin and PC-esterase domain family member 3
NXT2	nuclear transport factor 2 like export factor 2
OARD1	O-acyl-ADP-ribose deacylase 1
OAS2	2'-5'-oligoadenylate synthetase 2	Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling RSV-host interactions
OCEL1	occludin/ELL domain containing 1
OCIAD2	OCIA domain containing 2
ODAM	odontogenic, ameloblast associated	Amyloid fiber formation
ODF2	outer dense fiber of sperm tails 2	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
ODF2L	outer dense fiber of sperm tails 2 like
ODF4	outer dense fiber of sperm tails 4
OLFM1	olfactomedin 1
OLFM3	olfactomedin 3
OLFM4	olfactomedin 4	Neutrophil degranulation

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