Search Results for: TP53

1022 interactions involving TP53 - tumor protein p53 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel CSNK2A1 casein kinase 2 alpha 1
  • Synthesis of PC
  • WNT mediated activation of DVL
  • Condensation of Prometaphase Chromosomes
  • Signal transduction by L1
  • Regulation of TP53 Activity through Phosphorylation
  • Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
  • Receptor Mediated Mitophagy
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • Regulation of PTEN stability and activity
  • KEAP1-NFE2L2 pathway
  • Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
  • Maturation of hRSV A proteins
  • SPOP-mediated proteasomal degradation of PD-L1(CD274)
  • Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK
  • Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
  • ATP
  • (5-hydroxyindolo[1,2-a]quinazolin-7-yl)acetic acid
  • 1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One
  • Resveratrol
  • 1,8-Di-Hydroxy-4-Nitro-Anthraquinone
  • Benzamidine
  • 5,8-Di-Amino-1,4-Dihydroxy-Anthraquinone
  • Quercetin
  • Phosphoaminophosphonic Acid-Adenylate Ester
  • Tetrabromo-2-Benzotriazole
  • DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE
  • S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE
  • N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE
  • Emodin
  • 3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE
  • 19-(cyclopropylamino)-4,6,7,15-tetrahydro-5H-16,1-(azenometheno)-10,14-(metheno)pyrazolo[4,3-o][1,3,9]triazacyclohexadecin-8(9H)-one
  • N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE
  • 4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
  • 2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
  • 2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
  • 2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE
  • N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE
  • Dichlororibofuranosylbenzimidazole
  • Quinalizarin
  • Ellagic acid
  • Fostamatinib
Novel CSNK2B casein kinase 2 beta
  • Synthesis of PC
  • WNT mediated activation of DVL
  • Condensation of Prometaphase Chromosomes
  • Signal transduction by L1
  • Neutrophil degranulation
  • Regulation of TP53 Activity through Phosphorylation
  • Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
  • Receptor Mediated Mitophagy
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • Regulation of PTEN stability and activity
  • KEAP1-NFE2L2 pathway
  • Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
  • Maturation of hRSV A proteins
  • SPOP-mediated proteasomal degradation of PD-L1(CD274)
  • Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK
  • Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
  • ATP
  • Quercetin
Novel CUL4A cullin 4A
  • Recognition of DNA damage by PCNA-containing replication complex
  • DNA Damage Recognition in GG-NER
  • Formation of Incision Complex in GG-NER
  • Dual Incision in GG-NER
  • Formation of TC-NER Pre-Incision Complex
  • Transcription-Coupled Nucleotide Excision Repair (TC-NER)
  • Dual incision in TC-NER
  • Gap-filling DNA repair synthesis and ligation in TC-NER
  • Neddylation
Novel CUL7 cullin 7
  • XBP1(S) activates chaperone genes
  • Neddylation
  • Antigen processing: Ubiquitination & Proteasome degradation
  • 3M syndrome
Novel CUL9 cullin 9
  • Neddylation
Novel CXXC1 CXXC finger protein 1
  • XBP1(S) activates chaperone genes
  • Formation of WDR5-containing histone-modifying complexes
Novel DAPK3 death associated protein kinase 3
  • Caspase activation via Dependence Receptors in the absence of ligand
  • 2-tert-butyl-9-fluoro-1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one
  • 4-(6-{[(1R)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acid
  • (4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile
  • Fostamatinib
Novel DAXX death domain associated protein
  • SUMOylation of transcription cofactors
  • Regulation of TP53 Degradation
  • HCMV Early Events
  • Inhibition of DNA recombination at telomere
  • Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations
  • Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations
Novel DAZAP2 DAZ associated protein 2
Novel DCAF1 DDB1 and CUL4 associated factor 1
  • Antigen processing: Ubiquitination & Proteasome degradation
Novel DCST1 DC-STAMP domain containing 1
Novel DDRGK1 DDRGK domain containing 1
  • RHOA GTPase cycle
Novel DDX20 DEAD-box helicase 20
  • snRNP Assembly
  • SARS-CoV-2 modulates host translation machinery
Novel DDX5 DEAD-box helicase 5
  • SUMOylation of transcription cofactors
  • mRNA Splicing - Major Pathway
  • Estrogen-dependent gene expression
  • Replication of the SARS-CoV-1 genome
  • Replication of the SARS-CoV-2 genome
  • Artenimol
  • Prostate cancer
Novel DGKZ diacylglycerol kinase zeta
  • Effects of PIP2 hydrolysis
  • alpha-Tocopherol succinate
Novel DHCR24 24-dehydrocholesterol reductase
  • Cholesterol biosynthesis
  • Cholesterol biosynthesis via desmosterol
  • Cholesterol biosynthesis via lathosterol
  • Desmosterolosis
Novel DHFR dihydrofolate reductase
  • Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
  • Metabolism of folate and pterines
  • G1/S-Specific Transcription
  • NADH
  • Pyrimethamine
  • Methotrexate
  • Pemetrexed
  • Gentamicin
  • Proguanil
  • Trimetrexate
  • 2,4-Diamino-5-Methyl-6-[(3,4,5-Trimethoxy-N-Methylanilino)Methyl]Pyrido[2,3-D]Pyrimidine
  • 2,4-Diamino-6-[N-(2',5'-Dimethoxybenzyl)-N-Methylamino]Quinazoline
  • 6-(Octahydro-1h-Indol-1-Ylmethyl)Decahydroquinazoline-2,4-Diamine
  • N6-(2,5-Dimethoxy-Benzyl)-N6-Methyl-Pyrido[2,3-D]Pyrimidine-2,4,6-Triamine
  • 2,4-Diamino-6-[N-(3',4',5'-Trimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine
  • Sri-9662
  • 2,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-Ium
  • Sri-9439
  • Nicotinamide adenine dinucleotide phosphate
  • Piritrexim
  • Biopterin
  • 2,4-Diamino-6-[N-(3',5'-Dimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine
  • Iclaprim
  • Pralatrexate
  • 5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
  • 5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
  • 5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
  • 5-[(3R)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
  • 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine
  • [N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE
  • (4aS)-5-[(2,4-diaminopteridin-6-yl)methyl]-4a,5-dihydro-2H-dibenzo[b,f]azepin-8-ol
  • (2R,6S)-6-{[methyl(3,4,5-trimethoxyphenyl)amino]methyl}-1,2,5,6,7,8-hexahydroquinazoline-2,4-diamine
Novel DLEU1 deleted in lymphocytic leukemia 1
Novel DMTF1 cyclin D binding myb like transcription factor 1
Novel DNAJC7 DnaJ heat shock protein family (Hsp40) member C7
  • Regulation of HSF1-mediated heat shock response

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