Search Results for: STK11

276 interactions involving STK11 - serine/threonine kinase 11 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel SEPTIN9 septin 9
  • Hereditary neuralgic amyotrophy (HNA); Hereditary brachial plexus neuropathy
Novel SH3GL1 SH3 domain containing GRB2 like 1, endophilin A2
  • EGFR downregulation
  • Negative regulation of MET activity
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
  • InlB-mediated entry of Listeria monocytogenes into host cell
Novel SIK1 salt inducible kinase 1
  • Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes
  • Dabrafenib
  • Fostamatinib
Novel SIRT1 sirtuin 1
  • Regulation of HSF1-mediated heat shock response
  • SIRT1 negatively regulates rRNA expression
  • SIRT1 negatively regulates rRNA expression
  • Regulation of FOXO transcriptional activity by acetylation
  • Regulation of FOXO transcriptional activity by acetylation
  • Heme signaling
  • Negative Regulation of CDH1 Gene Transcription
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • Regulation of MITF-M dependent genes involved in metabolism
  • Transcriptional and post-translational regulation of MITF-M expression and activity
  • Expression of BMAL (ARNTL), CLOCK, and NPAS2
  • Resveratrol
  • Selisistat
  • Cambinol
Novel SKP2 S-phase kinase associated protein 2
  • APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
  • SCF(Skp2)-mediated degradation of p27/p21
  • Ub-specific processing proteases
  • Orc1 removal from chromatin
  • Cyclin D associated events in G1
  • Regulation of RUNX2 expression and activity
  • Neddylation
  • Aberrant regulation of mitotic exit in cancer due to RB1 defects
  • Regulation of BACH1 activity
  • Antigen processing: Ubiquitination & Proteasome degradation
Novel SMAD1 SMAD family member 1
  • Signaling by BMP
  • Ub-specific processing proteases
  • RUNX2 regulates bone development
  • Cardiogenesis
  • Transcriptional regulation of brown and beige adipocyte differentiation by EBF2
Novel SMARCA4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4
  • Interleukin-7 signaling
  • Formation of the beta-catenin:TCF transactivating complex
  • RMTs methylate histone arginines
  • Chromatin modifying enzymes
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • EGR2 and SOX10-mediated initiation of Schwann cell myelination
  • EGR2 and SOX10-mediated initiation of Schwann cell myelination
  • Negative Regulation of CDH1 Gene Transcription
  • Regulation of MITF-M-dependent genes involved in pigmentation
  • Regulation of MITF-M-dependent genes involved in pigmentation
  • Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
  • Formation of the canonical BAF (cBAF) complex
  • Formation of the polybromo-BAF (pBAF) complex
  • Formation of the embryonic stem cell BAF (esBAF) complex
  • Formation of the non-canonical BAF (ncBAF) complex
  • Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
  • Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Novel SNRK SNF related kinase
  • Fostamatinib
Novel SOX4 SRY-box transcription factor 4
  • Deactivation of the beta-catenin transactivating complex
Novel SPDEF SAM pointed domain containing ETS transcription factor
Novel ST14 ST14 transmembrane serine protease matriptase
  • Formation of the cornified envelope
  • Formation of the cornified envelope
  • Urokinase
  • Benzamidine
  • Camostat
  • Ichthyosis with hypotrichosis
Novel STK11IP serine/threonine kinase 11 interacting protein
  • Neutrophil degranulation
Novel STK24 serine/threonine kinase 24
  • Apoptotic cleavage of cellular proteins
  • Apoptotic execution phase
  • Fostamatinib
Novel STRADA STE20 related adaptor alpha
  • Energy dependent regulation of mTOR by LKB1-AMPK
Novel STRADB STE20 related adaptor beta
  • Energy dependent regulation of mTOR by LKB1-AMPK
Novel STX17 syntaxin 17
  • COPII-mediated vesicle transport
Novel TBC1D23 TBC1 domain family member 23
Novel TDRD7 tudor domain containing 7
Novel TEAD2 TEA domain transcription factor 2
  • YAP1- and WWTR1 (TAZ)-stimulated gene expression
  • RUNX3 regulates YAP1-mediated transcription
  • Formation of axial mesoderm
  • Regulation of PD-L1(CD274) transcription
Novel TERT telomerase reverse transcriptase
  • Telomere Extension By Telomerase
  • Formation of the beta-catenin:TCF transactivating complex
  • Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence
  • Zidovudine
  • Grn163l
  • Tertomotide
  • Cri du chat syndrome; Cat cry syndrome; Chromosme 5p deletion syndrome

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