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Novel |
H2AP |
H2A.P histone |
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Novel |
H3C1 |
H3 clustered histone 1 |
- Interleukin-7 signaling
- Interleukin-7 signaling
- Pre-NOTCH Transcription and Translation
- Formation of the beta-catenin:TCF transactivating complex
- PRC2 methylates histones and DNA
- Condensation of Prophase Chromosomes
- Oxidative Stress Induced Senescence
- Senescence-Associated Secretory Phenotype (SASP)
- HDACs deacetylate histones
- PKMTs methylate histone lysines
- HDMs demethylate histones
- HATs acetylate histones
- HATs acetylate histones
- RMTs methylate histone arginines
- Chromatin modifying enzymes
- SIRT1 negatively regulates rRNA expression
- ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
- NoRC negatively regulates rRNA expression
- NoRC negatively regulates rRNA expression
- B-WICH complex positively regulates rRNA expression
- DNA methylation
- Transcriptional regulation by small RNAs
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- Assembly of the ORC complex at the origin of replication
- RNA Polymerase I Promoter Opening
- RNA Polymerase I Promoter Escape
- RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- Estrogen-dependent gene expression
- Meiotic recombination
- HCMV Early Events
- HCMV Late Events
- Transcriptional regulation of granulopoiesis
- Defective pyroptosis
- Negative Regulation of CDH1 Gene Transcription
- Amyloid fiber formation
- Chromatin modifications during the maternal to zygotic transition (MZT)
- Factors involved in megakaryocyte development and platelet production
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
- Regulation of endogenous retroelements by KRAB-ZFP proteins
- Regulation of endogenous retroelements by KRAB-ZFP proteins
- Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
- Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
- Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
- Regulation of PD-L1(CD274) transcription
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Novel |
HACL2 |
2-hydroxyacyl-CoA lyase 2 |
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Novel |
HEY2 |
hes related family bHLH transcription factor with YRPW motif 2 |
- NOTCH1 Intracellular Domain Regulates Transcription
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- RUNX2 regulates osteoblast differentiation
- NOTCH3 Intracellular Domain Regulates Transcription
- NOTCH4 Intracellular Domain Regulates Transcription
- Cardiogenesis
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Novel |
HEYL |
hes related family bHLH transcription factor with YRPW motif like |
- NOTCH1 Intracellular Domain Regulates Transcription
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- NOTCH3 Intracellular Domain Regulates Transcription
- Regulation of CDH11 gene transcription
- Regulation of CDH11 gene transcription
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Novel |
HIVEP1 |
HIVEP zinc finger 1 |
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Novel |
HNRNPLL |
heterogeneous nuclear ribonucleoprotein L like |
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Novel |
HOTAIR |
HOX transcript antisense RNA |
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Novel |
HPCAL1 |
hippocalcin like 1 |
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Novel |
HSFX1 |
heat shock transcription factor family, X-linked 1 |
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Novel |
HSFY1 |
heat shock transcription factor Y-linked 1 |
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Novel |
HSFY2 |
heat shock transcription factor Y-linked 2 |
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Novel |
HSPA1A |
heat shock protein family A (Hsp70) member 1A |
- Viral RNP Complexes in the Host Cell Nucleus
- Regulation of HSF1-mediated heat shock response
- HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
- Attenuation phase
- HSF1-dependent transactivation
- AUF1 (hnRNP D0) binds and destabilizes mRNA
- Neutrophil degranulation
- PKR-mediated signaling
- Mitochondrial unfolded protein response (UPRmt)
- Regulation of HSF1-mediated heat shock response
- HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
- Attenuation phase
- HSF1-dependent transactivation
- Neutrophil degranulation
- PKR-mediated signaling
- Mitochondrial unfolded protein response (UPRmt)
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Novel |
IGF2R |
insulin like growth factor 2 receptor |
- Golgi Associated Vesicle Biogenesis
- Neutrophil degranulation
- Retrograde transport at the Trans-Golgi-Network
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
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- Mecasermin
- alpha-D-mannose 6-phosphate
- Cerliponase alfa
- Mecasermin rinfabate
- Avalglucosidase alfa
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Novel |
IL34 |
interleukin 34 |
- Other interleukin signaling
- Signaling by CSF1 (M-CSF) in myeloid cells
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Novel |
IMMT |
inner membrane mitochondrial protein |
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Novel |
IPO8 |
importin 8 |
- Transcriptional regulation by small RNAs
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Novel |
IST1 |
IST1 factor associated with ESCRT-III |
- Neutrophil degranulation
- Sealing of the nuclear envelope (NE) by ESCRT-III
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Novel |
ITGB4 |
integrin subunit beta 4 |
- Assembly of collagen fibrils and other multimeric structures
- Laminin interactions
- Syndecan interactions
- Type I hemidesmosome assembly
- Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
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- Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
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Novel |
KAT5 |
lysine acetyltransferase 5 |
- Formation of the beta-catenin:TCF transactivating complex
- Formation of the beta-catenin:TCF transactivating complex
- DNA Damage/Telomere Stress Induced Senescence
- HATs acetylate histones
- HDR through Single Strand Annealing (SSA)
- HDR through Homologous Recombination (HRR)
- Sensing of DNA Double Strand Breaks
- Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
- Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
- Resolution of D-loop Structures through Holliday Junction Intermediates
- Nonhomologous End-Joining (NHEJ)
- Homologous DNA Pairing and Strand Exchange
- Processing of DNA double-strand break ends
- Presynaptic phase of homologous DNA pairing and strand exchange
- Regulation of TP53 Activity through Phosphorylation
- G2/M DNA damage checkpoint
- Estrogen-dependent gene expression
- Defective homologous recombination repair (HRR) due to BRCA1 loss of function
- Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function
- Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
- Impaired BRCA2 binding to RAD51
- Impaired BRCA2 binding to PALB2
- Cardiogenesis
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- Coenzyme A
- S-Acetyl-Cysteine
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