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MCC |
MCC regulator of Wnt signaling pathway |
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MCEE |
methylmalonyl-CoA epimerase |
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- Methylmalonic aciduria (MMA)
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MCFD2 |
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit |
- COPII-mediated vesicle transport
- Cargo concentration in the ER
- Transport to the Golgi and subsequent modification
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- Antihemophilic factor, human recombinant
- Lonoctocog alfa
- Moroctocog alfa
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- Combined deficiency of factors V and VIII (F5F8D)
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MCM10 |
minichromosome maintenance 10 replication initiation factor |
- Activation of ATR in response to replication stress
- Activation of the pre-replicative complex
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MCM2 |
minichromosome maintenance complex component 2 |
- Activation of ATR in response to replication stress
- Unwinding of DNA
- Assembly of the pre-replicative complex
- Assembly of the pre-replicative complex
- Orc1 removal from chromatin
- Activation of the pre-replicative complex
- Switching of origins to a post-replicative state
- Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence
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MCM5 |
minichromosome maintenance complex component 5 |
- Activation of ATR in response to replication stress
- Unwinding of DNA
- Assembly of the pre-replicative complex
- Assembly of the pre-replicative complex
- Orc1 removal from chromatin
- Activation of the pre-replicative complex
- Switching of origins to a post-replicative state
- Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence
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MCM7 |
minichromosome maintenance complex component 7 |
- Activation of ATR in response to replication stress
- Unwinding of DNA
- Assembly of the pre-replicative complex
- Assembly of the pre-replicative complex
- Orc1 removal from chromatin
- Activation of the pre-replicative complex
- Switching of origins to a post-replicative state
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MCTP2 |
multiple C2 and transmembrane domain containing 2 |
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MDM2 |
MDM2 proto-oncogene |
- AKT phosphorylates targets in the cytosol
- Oxidative Stress Induced Senescence
- Oncogene Induced Senescence
- SUMOylation of transcription factors
- SUMOylation of ubiquitinylation proteins
- Trafficking of AMPA receptors
- Constitutive Signaling by AKT1 E17K in Cancer
- Ub-specific processing proteases
- Regulation of TP53 Activity through Phosphorylation
- Regulation of TP53 Degradation
- Regulation of TP53 Activity through Methylation
- Stabilization of p53
- Regulation of RUNX3 expression and activity
- Signaling by ALK fusions and activated point mutants
- Degradation of CDH1
- NPAS4 regulates expression of target genes
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- Zinc
- Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone
- Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
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- Penile cancer
- Alveolar rhabdomyosarcoma
- Choriocarcinoma
- Osteosarcoma
- Glioma
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MDM4 |
MDM4 regulator of p53 |
- Oxidative Stress Induced Senescence
- Oncogene Induced Senescence
- Ub-specific processing proteases
- Regulation of TP53 Activity through Phosphorylation
- Regulation of TP53 Degradation
- Regulation of TP53 Activity through Methylation
- Stabilization of p53
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MED11 |
mediator complex subunit 11 |
- PPARA activates gene expression
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
- RSV-host interactions
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MED19 |
mediator complex subunit 19 |
- PPARA activates gene expression
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
- RSV-host interactions
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MED24 |
mediator complex subunit 24 |
- PPARA activates gene expression
- Generic Transcription Pathway
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
- RSV-host interactions
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
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MED30 |
mediator complex subunit 30 |
- PPARA activates gene expression
- Generic Transcription Pathway
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
- RSV-host interactions
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
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MED8 |
mediator complex subunit 8 |
- PPARA activates gene expression
- Generic Transcription Pathway
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
- RSV-host interactions
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MED9 |
mediator complex subunit 9 |
- PPARA activates gene expression
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
- RSV-host interactions
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MEF2D |
myocyte enhancer factor 2D |
- Transcriptional activation of mitochondrial biogenesis
- Myogenesis
- NGF-stimulated transcription
- NGF-stimulated transcription
- Heme signaling
- Expression of BMAL (ARNTL), CLOCK, and NPAS2
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MEIS2 |
Meis homeobox 2 |
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MEOX1 |
mesenchyme homeobox 1 |
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MESD |
mesoderm development LRP chaperone |
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