Search Results for: UBC

1079 interactions involving UBC - ubiquitin C found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
VPS36 vacuolar protein sorting 36 homolog
  • Endosomal Sorting Complex Required For Transport (ESCRT)
  • HCMV Late Events
VPS37A VPS37A subunit of ESCRT-I
  • Budding and maturation of HIV virion
  • Membrane binding and targetting of GAG proteins
  • Endosomal Sorting Complex Required For Transport (ESCRT)
  • HCMV Late Events
  • Late endosomal microautophagy
VPS37B VPS37B subunit of ESCRT-I
  • Budding and maturation of HIV virion
  • Membrane binding and targetting of GAG proteins
  • Endosomal Sorting Complex Required For Transport (ESCRT)
  • HCMV Late Events
  • Late endosomal microautophagy
VPS37C VPS37C subunit of ESCRT-I
  • Budding and maturation of HIV virion
  • Membrane binding and targetting of GAG proteins
  • Endosomal Sorting Complex Required For Transport (ESCRT)
  • HCMV Late Events
  • Late endosomal microautophagy
VPS50 VPS50 subunit of EARP/GARPII complex
WAC WW domain containing adaptor with coiled-coil
  • E3 ubiquitin ligases ubiquitinate target proteins
WARS1 tryptophanyl-tRNA synthetase 1
  • Cytosolic tRNA aminoacylation
  • Tryptophan
  • Tryptophanyl-5'amp
  • Tryptophanamide
WBP2 WW domain binding protein 2
WDR33 WD repeat domain 33
  • Transport of Mature mRNA Derived from an Intronless Transcript
  • mRNA 3'-end processing
  • Processing of Capped Intron-Containing Pre-mRNA
  • RNA Polymerase II Transcription Termination
  • Processing of Intronless Pre-mRNAs
WDR48 WD repeat domain 48
  • Recognition of DNA damage by PCNA-containing replication complex
  • Ub-specific processing proteases
  • Fanconi Anemia Pathway
  • Signaling by cytosolic PDGFRA and PDGFRB fusion proteins
WDR5 WD repeat domain 5
  • PKMTs methylate histone lysines
  • HATs acetylate histones
  • HATs acetylate histones
  • RMTs methylate histone arginines
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • Neddylation
  • Cardiogenesis
  • Formation of WDR5-containing histone-modifying complexes
  • Epigenetic regulation of gene expression by MLL3 and MLL4 complexes
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • Regulation of PD-L1(CD274) transcription
  • Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome
WDR54 WD repeat domain 54
WDR6 WD repeat domain 6
  • RHOU GTPase cycle
  • RHOV GTPase cycle
  • RND3 GTPase cycle
  • RND2 GTPase cycle
  • RND1 GTPase cycle
WDR77 WD repeat domain 77
  • snRNP Assembly
  • RMTs methylate histone arginines
WFDC8 WAP four-disulfide core domain 8
WRNIP1 WRN helicase interacting protein 1
WWC1 WW and C2 domain containing 1
  • Signaling by Hippo
  • NOTCH3 Intracellular Domain Regulates Transcription
WWP1 WW domain containing E3 ubiquitin protein ligase 1
  • Downregulation of ERBB4 signaling
  • Stimuli-sensing channels
  • Regulation of RUNX2 expression and activity
  • Antigen processing: Ubiquitination & Proteasome degradation
WWP2 WW domain containing E3 ubiquitin protein ligase 2
  • Regulation of PTEN stability and activity
  • RHOQ GTPase cycle
  • RHOJ GTPase cycle
  • RHOU GTPase cycle
  • NOTCH3 Activation and Transmission of Signal to the Nucleus
XIAP X-linked inhibitor of apoptosis
  • Activation of caspases through apoptosome-mediated cleavage
  • SMAC (DIABLO) binds to IAPs
  • SMAC (DIABLO) binds to IAPs
  • SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
  • SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
  • SMAC, XIAP-regulated apoptotic response
  • Deactivation of the beta-catenin transactivating complex
  • RIPK1-mediated regulated necrosis
  • TNFR1-induced proapoptotic signaling
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • Regulation of necroptotic cell death
  • Regulation of PTEN localization
  • Regulation of PTEN stability and activity
  • Regulation of the apoptosome activity
  • 1-[3,3-Dimethyl-2-(2-Methylamino-Propionylamino)-Butyryl]-Pyrrolidine-2-Carboxylic Acid(1,2,3,4-Tetrahydro-Naphthalen-1-Yl)-Amide
  • Dequalinium
  • N-METHYLALANYL-3-METHYLVALYL-4-PHENOXY-N-(1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PROLINAMIDE
  • AEG35156
  • Terpinen-4-ol
  • Other well-defined immunodeficiency syndromes, including the following seven diseases: Wiskott-Aldrich syndrome; DiGeorge syndrome; Hyper-IgE syndrome; X-linked lymphoproliferative syndrome; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-linked Syndrome (IPEX); Cartilage-Hair Hypoplasia; Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)

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