Search Results for: APP

2116 interactions involving APP - amyloid beta precursor protein found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
LSMEM1 leucine rich single-pass membrane protein 1
LSMEM2 leucine rich single-pass membrane protein 2
LTV1 LTV1 ribosome biogenesis factor
  • Major pathway of rRNA processing in the nucleolus and cytosol
LUC7L2 LUC7 like 2, pre-mRNA splicing factor
LURAP1L leucine rich adaptor protein 1 like
LYPLA2 lysophospholipase 2
  • L1CAM interactions
LYRM7 LYR motif containing 7
  • Complex III assembly
MAB21L2 mab-21 like 2
MACROH2A1 macroH2A.1 histone
MAD2L1 mitotic arrest deficient 2 like 1
  • Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
  • Inactivation of APC/C via direct inhibition of the APC/C complex
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Cdc20:Phospho-APC/C mediated degradation of Cyclin A
  • APC/C:Cdc20 mediated degradation of mitotic proteins
  • APC-Cdc20 mediated degradation of Nek2A
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • RHO GTPases Activate Formins
  • Mitotic Prometaphase
  • EML4 and NUDC in mitotic spindle formation
MAG myelin associated glycoprotein
  • Axonal growth inhibition (RHOA activation)
  • Basigin interactions
  • EGR2 and SOX10-mediated initiation of Schwann cell myelination
MAGEA4 MAGE family member A4
MAGEH1 MAGE family member H1
MAIP1 matrix AAA peptidase interacting protein 1
  • Processing of SMDT1
MAK male germ cell associated kinase
MAP1LC3A microtubule associated protein 1 light chain 3 alpha
  • Macroautophagy
  • PINK1-PRKN Mediated Mitophagy
  • Receptor Mediated Mitophagy
MAP2 microtubule associated protein 2
  • Estramustine
  • Paclitaxel
  • Docetaxel
MAP2K3 mitogen-activated protein kinase kinase 3
  • Oxidative Stress Induced Senescence
  • activated TAK1 mediates p38 MAPK activation
  • Fostamatinib
  • Pimasertib
MAP2K4 mitogen-activated protein kinase kinase 4
  • Oxidative Stress Induced Senescence
  • Oxidative Stress Induced Senescence
  • FCERI mediated MAPK activation
  • JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
  • Uptake and function of anthrax toxins
  • MAP3K8 (TPL2)-dependent MAPK1/3 activation
  • Pimasertib
MAP3K11 mitogen-activated protein kinase kinase kinase 11
  • RAF activation
  • Signaling by moderate kinase activity BRAF mutants
  • Paradoxical activation of RAF signaling by kinase inactive BRAF
  • CDC42 GTPase cycle
  • RHOG GTPase cycle
  • RHOV GTPase cycle
  • Signaling downstream of RAS mutants
  • Fostamatinib

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