MUC1 - Wiki-MPM

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	MALL	mal, T cell differentiation protein like
Novel	MARCHF2	membrane associated ring-CH-type finger 2
Novel	MIP	major intrinsic protein of lens fiber	Passive transport by Aquaporins	B-nonylglucoside
Novel	MYADM	myeloid associated differentiation marker
Novel	NDUFA3	NADH:ubiquinone oxidoreductase subunit A3	Respiratory electron transport Complex I biogenesis	NADH
Novel	NEU1	neuraminidase 1	Sialic acid metabolism Defective NEU1 causes sialidosis Neutrophil degranulation Glycosphingolipid catabolism	Oseltamivir Celecoxib Acetylsalicylic acid	Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD) Sialidosis; Mucolipidosis I Galactosialidosis
Novel	NINJ1	ninjurin 1
Novel	NINJ2	ninjurin 2
Novel	NKG7	natural killer cell granule protein 7
Novel	NUP62	nucleoporin 62	ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation SARS-CoV-2 activates/modulates innate and adaptive immune responses
Novel	OAZ1	ornithine decarboxylase antizyme 1	Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines	Ornithine
Novel	OR10AG1	olfactory receptor family 10 subfamily AG member 1	Expression and translocation of olfactory receptors
Novel	OSGEP	O-sialoglycoprotein endopeptidase	tRNA modification in the nucleus and cytosol
Novel	PAQR6	progestin and adipoQ receptor family member 6
Novel	PKLR	pyruvate kinase L/R		Pyruvic acid 2-Phosphoglycolic Acid beta-D-fructofuranose 1,6-bisphosphate Mitapivat	Pyruvate kinase (PK) deficiency, including: Red cell pyruvate kinase (PK) deficiency; Pyruvate kinase hyperactivity
Novel	PLN	phospholamban	Ion homeostasis Ion transport by P-type ATPases
Novel	PLP1	proteolipid protein 1			Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD) Hereditary spastic paraplegia (SPG)
Novel	PLP2	proteolipid protein 2
Novel	PLPP6	phospholipid phosphatase 6	Cholesterol biosynthesis
Novel	PNLIPRP1	pancreatic lipase related protein 1	Digestion of dietary lipid

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