Search Results for: UBC

1079 interactions involving UBC - ubiquitin C found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
UCHL5 ubiquitin C-terminal hydrolase L5
  • Downregulation of TGF-beta receptor signaling
  • UCH proteinases
  • UCH proteinases
UEVLD UEV and lactate/malate dehyrogenase domains
UFD1 ubiquitin recognition factor in ER associated degradation 1
  • Translesion Synthesis by POLH
  • Ub-specific processing proteases
  • Neddylation
  • KEAP1-NFE2L2 pathway
  • Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
  • Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
UGP2 UDP-glucose pyrophosphorylase 2
  • Formation of the active cofactor, UDP-glucuronate
  • Glycogen synthesis
UHRF1 ubiquitin like with PHD and ring finger domains 1
  • DNA methylation
  • Chromatin modifications during the maternal to zygotic transition (MZT)
UIMC1 ubiquitin interaction motif containing 1
  • Metalloprotease DUBs
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • G2/M DNA damage checkpoint
ULK1 unc-51 like autophagy activating kinase 1
  • Macroautophagy
  • Regulation of TNFR1 signaling
  • TBC/RABGAPs
  • RAB GEFs exchange GTP for GDP on RABs
  • Receptor Mediated Mitophagy
  • Fostamatinib
ULK3 unc-51 like kinase 3
  • Hedgehog 'on' state
  • Fostamatinib
UNC79 unc-79 subunit of NALCN channel complex
  • Stimuli-sensing channels
UNC93B3 unc-93 homolog B3 (pseudogene)
UQCRQ ubiquinol-cytochrome c reductase complex III subunit VII
  • Respiratory electron transport
  • Mitochondrial protein degradation
  • Complex III assembly
  • Complex III assembly
  • 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
  • 6-Hydroxy-5-undecyl-4,7-benzothiazoledione
  • Azoxystrobin
  • (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE
  • (S)-famoxadone
  • METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE
  • 2-Nonyl-4-quinolinol 1-oxide
  • Ubiquinone Q2
  • Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
USP1 ubiquitin specific peptidase 1
  • Recognition of DNA damage by PCNA-containing replication complex
  • Fanconi Anemia Pathway
USP10 ubiquitin specific peptidase 10
  • Termination of translesion DNA synthesis
  • Ub-specific processing proteases
USP11 ubiquitin specific peptidase 11
USP12 ubiquitin specific peptidase 12
  • Ub-specific processing proteases
USP13 ubiquitin specific peptidase 13
  • Ub-specific processing proteases
  • Regulation of PTEN stability and activity
USP14 ubiquitin specific peptidase 14
  • Ub-specific processing proteases
  • Regulation of NF-kappa B signaling
  • Phenethyl Isothiocyanate
USP15 ubiquitin specific peptidase 15
  • Downregulation of TGF-beta receptor signaling
  • UCH proteinases
  • Ub-specific processing proteases
USP16 ubiquitin specific peptidase 16
  • Ub-specific processing proteases
USP17L2 ubiquitin specific peptidase 17 like family member 2
  • Ub-specific processing proteases
  • RAS processing

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