Search Results for: APP

2116 interactions involving APP - amyloid beta precursor protein found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
LARP4 La ribonucleoprotein 4
LARP6 La ribonucleoprotein 6, translational regulator
LARP7 La ribonucleoprotein 7, transcriptional regulator
LATS1 large tumor suppressor kinase 1
  • Signaling by Hippo
  • Fostamatinib
LCP2 lymphocyte cytosolic protein 2
  • GPVI-mediated activation cascade
  • Generation of second messenger molecules
  • Generation of second messenger molecules
  • DAP12 signaling
  • FCERI mediated MAPK activation
  • FCERI mediated Ca+2 mobilization
  • FCERI mediated Ca+2 mobilization
LDLRAP1 low density lipoprotein receptor adaptor protein 1
  • Vitamin D (calciferol) metabolism
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
  • Chylomicron clearance
  • LDL clearance
  • Transport of RCbl within the body
LENG1 leukocyte receptor cluster member 1
  • mRNA Splicing - Major Pathway
LETM2 leucine zipper and EF-hand containing transmembrane protein 2
LETMD1 LETM1 domain containing 1
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  • Pre-NOTCH Processing in Golgi
  • Defective LFNG causes SCDO3
  • Somitogenesis
  • Nephron development
  • Spondylocostal dysostosis (SCD)
LGALS2 galectin 2
  • Beta-D-Glucose
LGALS3 galectin 3
  • Neutrophil degranulation
  • Advanced glycosylation endproduct receptor signaling
  • RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
  • RUNX2 regulates genes involved in differentiation of myeloid cells
  • 2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide
  • Lactose
LIG3 DNA ligase 3
  • Resolution of AP sites via the single-nucleotide replacement pathway
  • APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway
  • HDR through MMEJ (alt-NHEJ)
  • Gap-filling DNA repair synthesis and ligation in GG-NER
  • Gap-filling DNA repair synthesis and ligation in TC-NER
  • Bleomycin
LIMA1 LIM domain and actin binding 1
LIMCH1 LIM and calponin homology domains 1
LIMD1 LIM domain containing 1
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
LIMK1 LIM domain kinase 1
  • Regulation of actin dynamics for phagocytic cup formation
  • Regulation of actin dynamics for phagocytic cup formation
  • EPHB-mediated forward signaling
  • Sema3A PAK dependent Axon repulsion
  • Sema3A PAK dependent Axon repulsion
  • Sema4D induced cell migration and growth-cone collapse
  • RHO GTPases Activate ROCKs
  • RHO GTPases activate PAKs
  • Dabrafenib
  • Fostamatinib
LIMS2 LIM zinc finger domain containing 2
  • Cell-extracellular matrix interactions
LIN7A lin-7 cell polarity scaffold A
  • Dopamine Neurotransmitter Release Cycle
  • Neurexins and neuroligins
  • Assembly and cell surface presentation of NMDA receptors
LINC00663 long intergenic non-protein coding RNA 663

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