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UBA2 |
ubiquitin like modifier activating enzyme 2 |
- SUMO is conjugated to E1 (UBA2:SAE1)
- SUMO is conjugated to E1 (UBA2:SAE1)
- SUMO is transferred from E1 to E2 (UBE2I, UBC9)
- SUMO is transferred from E1 to E2 (UBE2I, UBC9)
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UBA6 |
ubiquitin like modifier activating enzyme 6 |
- Synthesis of active ubiquitin: roles of E1 and E2 enzymes
- Synthesis of active ubiquitin: roles of E1 and E2 enzymes
- Antigen processing: Ubiquitination & Proteasome degradation
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UBAC1 |
UBA domain containing 1 |
- Antigen processing: Ubiquitination & Proteasome degradation
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UBAC2 |
UBA domain containing 2 |
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UBAP1 |
ubiquitin associated protein 1 |
- Budding and maturation of HIV virion
- Membrane binding and targetting of GAG proteins
- Endosomal Sorting Complex Required For Transport (ESCRT)
- HCMV Late Events
- Late endosomal microautophagy
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UBAP2 |
ubiquitin associated protein 2 |
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UBASH3A |
ubiquitin associated and SH3 domain containing A |
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UBASH3B |
ubiquitin associated and SH3 domain containing B |
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UBE2A |
ubiquitin conjugating enzyme E2 A |
- Synthesis of active ubiquitin: roles of E1 and E2 enzymes
- E3 ubiquitin ligases ubiquitinate target proteins
- Antigen processing: Ubiquitination & Proteasome degradation
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UBE2C |
ubiquitin conjugating enzyme E2 C |
- Inactivation of APC/C via direct inhibition of the APC/C complex
- APC/C:Cdc20 mediated degradation of Cyclin B
- Autodegradation of Cdh1 by Cdh1:APC/C
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
- Regulation of APC/C activators between G1/S and early anaphase
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Phosphorylation of the APC/C
- APC-Cdc20 mediated degradation of Nek2A
- Separation of Sister Chromatids
- Senescence-Associated Secretory Phenotype (SASP)
- Assembly of the pre-replicative complex
- CDK-mediated phosphorylation and removal of Cdc6
- Transcriptional Regulation by VENTX
- Synthesis of active ubiquitin: roles of E1 and E2 enzymes
- Aberrant regulation of mitotic exit in cancer due to RB1 defects
- Antigen processing: Ubiquitination & Proteasome degradation
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UBE2D1 |
ubiquitin conjugating enzyme E2 D1 |
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
- Inactivation of APC/C via direct inhibition of the APC/C complex
- TICAM1, RIP1-mediated IKK complex recruitment
- APC/C:Cdc20 mediated degradation of Cyclin B
- Autodegradation of Cdh1 by Cdh1:APC/C
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
- Regulation of APC/C activators between G1/S and early anaphase
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Phosphorylation of the APC/C
- APC-Cdc20 mediated degradation of Nek2A
- Signaling by BMP
- Downstream TCR signaling
- Downregulation of SMAD2/3:SMAD4 transcriptional activity
- Separation of Sister Chromatids
- Senescence-Associated Secretory Phenotype (SASP)
- FCERI mediated NF-kB activation
- Regulation of TNFR1 signaling
- CLEC7A (Dectin-1) signaling
- Ovarian tumor domain proteases
- Assembly of the pre-replicative complex
- CDK-mediated phosphorylation and removal of Cdc6
- Transcriptional Regulation by VENTX
- Synthesis of active ubiquitin: roles of E1 and E2 enzymes
- E3 ubiquitin ligases ubiquitinate target proteins
- Neddylation
- Peroxisomal protein import
- Negative regulators of DDX58/IFIH1 signaling
- IKK complex recruitment mediated by RIP1
- Aberrant regulation of mitotic exit in cancer due to RB1 defects
- Inactivation of CSF3 (G-CSF) signaling
- Antigen processing: Ubiquitination & Proteasome degradation
- Degradation of CRY and PER proteins
- Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
- ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
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UBE2D3 |
ubiquitin conjugating enzyme E2 D3 |
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
- TICAM1, RIP1-mediated IKK complex recruitment
- Signaling by BMP
- Downregulation of SMAD2/3:SMAD4 transcriptional activity
- PINK1-PRKN Mediated Mitophagy
- Regulation of TNFR1 signaling
- E3 ubiquitin ligases ubiquitinate target proteins
- Neddylation
- Peroxisomal protein import
- Negative regulators of DDX58/IFIH1 signaling
- IKK complex recruitment mediated by RIP1
- Inactivation of CSF3 (G-CSF) signaling
- Antigen processing: Ubiquitination & Proteasome degradation
- ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
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UBE2D4 |
ubiquitin conjugating enzyme E2 D4 |
- Antigen processing: Ubiquitination & Proteasome degradation
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UBE2E1 |
ubiquitin conjugating enzyme E2 E1 |
- ISG15 antiviral mechanism
- Inactivation of APC/C via direct inhibition of the APC/C complex
- APC/C:Cdc20 mediated degradation of Cyclin B
- Autodegradation of Cdh1 by Cdh1:APC/C
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
- Regulation of APC/C activators between G1/S and early anaphase
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Phosphorylation of the APC/C
- APC-Cdc20 mediated degradation of Nek2A
- Separation of Sister Chromatids
- Senescence-Associated Secretory Phenotype (SASP)
- Assembly of the pre-replicative complex
- CDK-mediated phosphorylation and removal of Cdc6
- Transcriptional Regulation by VENTX
- Synthesis of active ubiquitin: roles of E1 and E2 enzymes
- E3 ubiquitin ligases ubiquitinate target proteins
- Aberrant regulation of mitotic exit in cancer due to RB1 defects
- Antigen processing: Ubiquitination & Proteasome degradation
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UBE2E3 |
ubiquitin conjugating enzyme E2 E3 |
- Synthesis of active ubiquitin: roles of E1 and E2 enzymes
- Antigen processing: Ubiquitination & Proteasome degradation
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UBE2G1 |
ubiquitin conjugating enzyme E2 G1 |
- Synthesis of active ubiquitin: roles of E1 and E2 enzymes
- Antigen processing: Ubiquitination & Proteasome degradation
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UBE2G2 |
ubiquitin conjugating enzyme E2 G2 |
- Synthesis of active ubiquitin: roles of E1 and E2 enzymes
- Antigen processing: Ubiquitination & Proteasome degradation
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UBE2J1 |
ubiquitin conjugating enzyme E2 J1 |
- Antigen processing: Ubiquitination & Proteasome degradation
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UBE2J2 |
ubiquitin conjugating enzyme E2 J2 |
- E3 ubiquitin ligases ubiquitinate target proteins
- Antigen processing: Ubiquitination & Proteasome degradation
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UBE2L3 |
ubiquitin conjugating enzyme E2 L3 |
- PINK1-PRKN Mediated Mitophagy
- Regulation of TNFR1 signaling
- Regulation of necroptotic cell death
- Synthesis of active ubiquitin: roles of E1 and E2 enzymes
- E3 ubiquitin ligases ubiquitinate target proteins
- Antigen processing: Ubiquitination & Proteasome degradation
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