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LINC01554 |
long intergenic non-protein coding RNA 1554 |
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MAP7D3 |
MAP7 domain containing 3 |
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MAPT |
microtubule associated protein tau |
- Caspase-mediated cleavage of cytoskeletal proteins
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- Lansoprazole
- Astemizole
- Paclitaxel
- Docetaxel
- Flortaucipir F-18
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- Progressive supranuclear palsy (PSP); Steele-Richardson-Olszewski syndrome
- Frontotemporal lobar degeneration (FTLD), including: Pick disease of brain; Frontotemporal dementia (FTD); Ubiquitin-positive frontotemporal dementia (UP-FTD); Progressive supranuclear palsy type 1 (PSNP1); Inclusion body myopathy with early-onset paget disease and frontotemporal dementia (IBMPFD); Frontotemporal dementia, chromosome 3-linked (FTD3)
- Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
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MRPL28 |
mitochondrial ribosomal protein L28 |
- Mitochondrial translation initiation
- Mitochondrial translation elongation
- Mitochondrial translation elongation
- Mitochondrial translation termination
- Mitochondrial ribosome-associated quality control
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MTCL1 |
microtubule crosslinking factor 1 |
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MTDH |
metadherin |
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MVD |
mevalonate diphosphate decarboxylase |
- Cholesterol biosynthesis
- Activation of gene expression by SREBF (SREBP)
- Synthesis of dolichyl-phosphate
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OGT |
O-linked N-acetylglucosamine (GlcNAc) transferase |
- HATs acetylate histones
- RIPK1-mediated regulated necrosis
- Regulation of necroptotic cell death
- UCH proteinases
- Formation of WDR5-containing histone-modifying complexes
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PHIP |
PHIP subunit of CUL4-Ring ligase complex |
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PIEZO1 |
piezo type mechanosensitive ion channel component 1 (Er blood group) |
- High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
- Mechanical load activates signaling by PIEZO1 and integrins in osteocytes
- Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
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PLK1 |
polo like kinase 1 |
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
- Polo-like kinase mediated events
- Golgi Cisternae Pericentriolar Stack Reorganization
- Golgi Cisternae Pericentriolar Stack Reorganization
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Phosphorylation of the APC/C
- Phosphorylation of Emi1
- Condensation of Prophase Chromosomes
- Separation of Sister Chromatids
- Resolution of Sister Chromatid Cohesion
- Regulation of PLK1 Activity at G2/M Transition
- Activation of NIMA Kinases NEK9, NEK6, NEK7
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Anchoring of the basal body to the plasma membrane
- RHO GTPases Activate Formins
- Mitotic Prometaphase
- Mitotic Metaphase/Anaphase Transition
- Mitotic Telophase/Cytokinesis
- Cyclin A/B1/B2 associated events during G2/M transition
- The role of GTSE1 in G2/M progression after G2 checkpoint
- AURKA Activation by TPX2
- EML4 and NUDC in mitotic spindle formation
- Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
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- 3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol
- 3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide
- 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE
- 1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino]ethyl]-1,3-thiazol-2-yl]urea
- Wortmannin
- Fostamatinib
- Volasertib
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PRDM7 |
PR/SET domain 7 |
- Generic Transcription Pathway
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RCC1 |
regulator of chromosome condensation 1 |
- Rev-mediated nuclear export of HIV RNA
- Nuclear import of Rev protein
- Postmitotic nuclear pore complex (NPC) reformation
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RILPL2 |
Rab interacting lysosomal protein like 2 |
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ROBO1 |
roundabout guidance receptor 1 |
- Netrin-1 signaling
- Signaling by ROBO receptors
- Signaling by ROBO receptors
- Activation of RAC1
- Regulation of commissural axon pathfinding by SLIT and ROBO
- Regulation of commissural axon pathfinding by SLIT and ROBO
- Inactivation of CDC42 and RAC1
- Role of ABL in ROBO-SLIT signaling
- Role of ABL in ROBO-SLIT signaling
- SLIT2:ROBO1 increases RHOA activity
- Regulation of cortical dendrite branching
- Regulation of expression of SLITs and ROBOs
- Regulation of expression of SLITs and ROBOs
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RSPH1 |
radial spoke head component 1 |
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SCGN |
secretagogin, EF-hand calcium binding protein |
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SEL1L3 |
SEL1L family member 3 |
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SLC7A5 |
solute carrier family 7 member 5 |
- Basigin interactions
- Amino acid transport across the plasma membrane
- Tryptophan catabolism
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SMN1 |
survival of motor neuron 1, telomeric |
- snRNP Assembly
- SARS-CoV-2 modulates host translation machinery
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- Spinal muscular atrophy (SMA), including: SMA type I (SMA1) / Werdning-Hoffman disease; SMA type II (SMA2); SMA type III (SMA3) / Kugeleberg-Welander disease; SMA type IV (SMA4); X-linked SMA 2 (SMAX2); X-linked distal SMA 3 (DSMAX); Distal SMA autosomal recessive type 4 (DSMA4); Congenital distal spinal muscular atrophy (SMAL); SMA proximal adult autosomal dominant (SMAPAD)
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