PTEN - Wiki-MPM

Novel	Interactant Symbol	Name	Associated Pathways Hide	Associated Diseases Hide
Novel	DAP3	death associated protein 3	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Novel	DAXX	death domain associated protein	SUMOylation of transcription cofactors Regulation of TP53 Degradation HCMV Early Events Inhibition of DNA recombination at telomere Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations
Novel	DBN1	drebrin 1	RHOD GTPase cycle RHOH GTPase cycle RHOBTB2 GTPase cycle RHOBTB1 GTPase cycle
Novel	DCAF11	DDB1 and CUL4 associated factor 11	Neddylation
Novel	DCAF13	DDB1 and CUL4 associated factor 13	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol Neddylation
Novel	DDB1	damage specific DNA binding protein 1	Recognition of DNA damage by PCNA-containing replication complex DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER Dual Incision in GG-NER Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Neddylation	Disorders of nucleotide excision repair, including: Xeroderma pigmentosum (XP); Cockayne syndrome (CS); UV-sensitive syndrome (UVS); Trichothiodystrophy (TTD); Cerebro-oculo-facio-skeletal syndrome (COFS); XFE progeroid syndrome
Novel	DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	SRP-dependent cotranslational protein targeting to membrane Asparagine N-linked glycosylation Neutrophil degranulation Advanced glycosylation endproduct receptor signaling Maturation of spike protein Regulation of CDH1 posttranslational processing and trafficking to plasma membrane PD-L1(CD274) glycosylation and translocation to plasma membrane
Novel	DDX1	DEAD-box helicase 1	tRNA processing in the nucleus
Novel	DDX21	DExD-box helicase 21	B-WICH complex positively regulates rRNA expression Major pathway of rRNA processing in the nucleolus and cytosol
Novel	DDX24	DEAD-box helicase 24
Novel	DDX47	DEAD-box helicase 47	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Novel	DDX50	DExD-box helicase 50
Novel	DHX15	DEAH-box helicase 15	mRNA Splicing - Major Pathway
Novel	DHX9	DExH-box helicase 9	RIP-mediated NFkB activation via ZBP1 DEx/H-box helicases activate type I IFN and inflammatory cytokines production mRNA Splicing - Major Pathway PKR-mediated signaling
Novel	DLC1	DLC1 Rho GTPase activating protein	RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOQ GTPase cycle
Novel	DLG1	discs large MAGUK scaffold protein 1	Trafficking of AMPA receptors Unblocking of NMDA receptors, glutamate binding and activation Unblocking of NMDA receptors, glutamate binding and activation Ras activation upon Ca2+ influx through NMDA receptor NrCAM interactions Activation of Ca-permeable Kainate Receptor RAF/MAP kinase cascade Synaptic adhesion-like molecules Assembly and cell surface presentation of NMDA receptors Negative regulation of NMDA receptor-mediated neuronal transmission Long-term potentiation
Novel	DNAJA1	DnaJ heat shock protein family (Hsp40) member A1	HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Mitochondrial unfolded protein response (UPRmt)
Novel	DNAJA2	DnaJ heat shock protein family (Hsp40) member A2	HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Novel	DNAJA3	DnaJ heat shock protein family (Hsp40) member A3
Novel	DNAJB6	DnaJ heat shock protein family (Hsp40) member B6	Regulation of HSF1-mediated heat shock response

Search Results for: PTEN