Search Results for: PTEN

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
SPTBN1 spectrin beta, non-erythrocytic 1
  • Nephrin family interactions
  • NCAM signaling for neurite out-growth
  • NCAM signaling for neurite out-growth
  • Interaction between L1 and Ankyrins
  • Interaction between L1 and Ankyrins
  • RAF/MAP kinase cascade
  • COPI-mediated anterograde transport
  • RHOU GTPase cycle
  • RHOV GTPase cycle
  • Sensory processing of sound by inner hair cells of the cochlea
  • Sensory processing of sound by outer hair cells of the cochlea
  • Signaling by FLT3 fusion proteins
  • Signaling by FLT3 fusion proteins
  • Calcium
  • 1D-myo-inositol 1,4,5-trisphosphate
SRP14 signal recognition particle 14
  • SRP-dependent cotranslational protein targeting to membrane
  • SRP-dependent cotranslational protein targeting to membrane
  • Neutrophil degranulation
  • Artenimol
SSB small RNA binding exonuclease protection factor La
  • RNA Polymerase III Transcription Termination
  • RNA Polymerase III Abortive And Retractive Initiation
SSR4 signal sequence receptor subunit 4
  • SRP-dependent cotranslational protein targeting to membrane
SSRP1 structure specific recognition protein 1
  • Formation of RNA Pol II elongation complex
  • Formation of HIV elongation complex in the absence of HIV Tat
  • Formation of HIV-1 elongation complex containing HIV-1 Tat
  • Pausing and recovery of Tat-mediated HIV elongation
  • Tat-mediated HIV elongation arrest and recovery
  • Tat-mediated elongation of the HIV-1 transcript
  • HIV elongation arrest and recovery
  • Pausing and recovery of HIV elongation
  • RNA Polymerase II Pre-transcription Events
  • TP53 Regulates Transcription of DNA Repair Genes
  • Regulation of TP53 Activity through Phosphorylation
  • RNA Polymerase II Transcription Elongation
STAG2 STAG2 cohesin complex component
  • Meiotic synapsis
  • Separation of Sister Chromatids
  • Establishment of Sister Chromatid Cohesion
  • Cohesin Loading onto Chromatin
  • Resolution of Sister Chromatid Cohesion
  • SUMOylation of DNA damage response and repair proteins
  • Estrogen-dependent gene expression
STK11 serine/threonine kinase 11
  • AMPK inhibits chREBP transcriptional activation activity
  • Energy dependent regulation of mTOR by LKB1-AMPK
  • Regulation of TP53 Activity through Phosphorylation
  • FOXO-mediated transcription of cell death genes
  • Peutz-Jeghers syndrome
  • Pancreatic cancer
STRAP serine/threonine kinase receptor associated protein
  • Downregulation of TGF-beta receptor signaling
  • Downregulation of TGF-beta receptor signaling
  • Positive Regulation of CDH1 Gene Transcription
SUDS3 SIN3A corepressor complex component SDS3
  • HDACs deacetylate histones
  • NoRC negatively regulates rRNA expression
  • Ub-specific processing proteases
  • Potential therapeutics for SARS
SUGP2 SURP and G-patch domain containing 2
TCF25 TCF25 ribosome quality control complex subunit
  • Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
  • Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
TCP1 t-complex 1
  • Prefoldin mediated transfer of substrate to CCT/TriC
  • Formation of tubulin folding intermediates by CCT/TriC
  • Folding of actin by CCT/TriC
  • Association of TriC/CCT with target proteins during biosynthesis
  • Association of TriC/CCT with target proteins during biosynthesis
  • BBSome-mediated cargo-targeting to cilium
  • Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
  • Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
TECR trans-2,3-enoyl-CoA reductase
  • Synthesis of very long-chain fatty acyl-CoAs
TERF2IP TERF2 interacting protein
  • Recognition and association of DNA glycosylase with site containing an affected pyrimidine
  • Cleavage of the damaged pyrimidine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Cleavage of the damaged purine
  • Cleavage of the damaged purine
  • Meiotic synapsis
  • Packaging Of Telomere Ends
  • Telomere Extension By Telomerase
  • Polymerase switching on the C-strand of the telomere
  • Processive synthesis on the C-strand of the telomere
  • Telomere C-strand (Lagging Strand) Synthesis
  • Telomere C-strand synthesis initiation
  • Removal of the Flap Intermediate from the C-strand
  • DNA Damage/Telomere Stress Induced Senescence
  • Inhibition of DNA recombination at telomere
THOC2 THO complex subunit 2
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
  • mRNA 3'-end processing
  • RNA Polymerase II Transcription Termination
THOC3 THO complex subunit 3
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
  • mRNA 3'-end processing
  • RNA Polymerase II Transcription Termination
THOC6 THO complex subunit 6
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
  • mRNA 3'-end processing
  • RNA Polymerase II Transcription Termination
TMEFF1 transmembrane protein with EGF like and two follistatin like domains 1
TNKS tankyrase
  • TCF dependent signaling in response to WNT
  • Degradation of AXIN
  • XAV939 stabilizes AXIN
  • Ub-specific processing proteases
  • Regulation of PTEN stability and activity
TNKS2 tankyrase 2
  • TCF dependent signaling in response to WNT
  • Degradation of AXIN
  • XAV939 stabilizes AXIN
  • Ub-specific processing proteases
  • Regulation of PTEN stability and activity

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