Search Results for: APP

2116 interactions involving APP - amyloid beta precursor protein found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
GAS2 growth arrest specific 2
  • Caspase-mediated cleavage of cytoskeletal proteins
GATD1 glutamine amidotransferase class 1 domain containing 1
GATD3 glutamine amidotransferase class 1 domain containing 3
GBA2 glucosylceramidase beta 2
  • Glycosphingolipid catabolism
GCC1 GRIP and coiled-coil domain containing 1
  • Retrograde transport at the Trans-Golgi-Network
GEMIN8 gem nuclear organelle associated protein 8
  • snRNP Assembly
  • SARS-CoV-2 modulates host translation machinery
GFAP glial fibrillary acidic protein
  • Nuclear signaling by ERBB4
  • Chaperone Mediated Autophagy
  • Alexander disease
GGA1 golgi associated, gamma adaptin ear containing, ARF binding protein 1
  • TBC/RABGAPs
  • Amyloid fiber formation
GGA2 golgi associated, gamma adaptin ear containing, ARF binding protein 2
  • TBC/RABGAPs
  • Amyloid fiber formation
GGCT gamma-glutamylcyclotransferase
  • Glutathione synthesis and recycling
GIMAP4 GTPase, IMAP family member 4
GIMAP5 GTPase, IMAP family member 5
GIMAP6 GTPase, IMAP family member 6
GIMAP8 GTPase, IMAP family member 8
GJB1 gap junction protein beta 1
  • Oligomerization of connexins into connexons
  • Oligomerization of connexins into connexons
  • Transport of connexins along the secretory pathway
  • Gap junction assembly
  • Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GLB1L galactosidase beta 1 like
  • Keratan sulfate degradation
  • CS/DS degradation
  • Glycosphingolipid catabolism
GLOD4 glyoxalase domain containing 4
GLRB glycine receptor beta
  • Neurotransmitter receptors and postsynaptic signal transmission
  • Neurotransmitter receptors and postsynaptic signal transmission
  • Glycine
  • Lindane
  • Memantine
  • Seletracetam
  • Cannabidiol
  • Medical Cannabis
  • Nabiximols
  • Hyperekplexia
GLRX5 glutaredoxin 5
  • Mitochondrial iron-sulfur cluster biogenesis
  • Sideroblastic anemia, including: Pyridoxine-refractory autosomal recessive sideroblastic anemia (PRARSA); X-linked sideroblastic anemia (XLSA); X-linked sideroblastic anemia with ataxia (ASAT)
  • Erythropoietic porphyria (EP), including: Erythropoietic protoporphyria (EPP); Congenital erythropoietic porphyria (CEP); Gunther Disease; X-linked erythropoietic protoporphyria (XLEPP)
GNA12 G protein subunit alpha 12
  • G alpha (12/13) signalling events
  • Thrombin signalling through proteinase activated receptors (PARs)
  • Thrombin signalling through proteinase activated receptors (PARs)

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