APP - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
FAM27E3	family with sequence similarity 27 member E3
FAM32A	family with sequence similarity 32 member A	mRNA Splicing - Major Pathway
FAM3A	FAM3 metabolism regulating signaling molecule A
FAM3B	FAM3 metabolism regulating signaling molecule B
FAM47B	family with sequence similarity 47 member B
FAM50A	family with sequence similarity 50 member A	mRNA Splicing - Major Pathway
FAM53A	family with sequence similarity 53 member A
FAM90A1	family with sequence similarity 90 member A1
FANCI	FA complementation group I	Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes		Fanconi anemia
FANCM	FA complementation group M	Fanconi Anemia Pathway PKR-mediated signaling		Fanconi anemia
FBF1	Fas binding factor 1	Anchoring of the basal body to the plasma membrane
FBLN1	fibulin 1	Molecules associated with elastic fibres Molecules associated with elastic fibres		Synpolydactyly, 3/3'4, associated with metacarpal and metatarsal synostoses
FBXL2	F-box and leucine rich repeat protein 2
FBXL7	F-box and leucine rich repeat protein 7	FBXL7 down-regulates AURKA during mitotic entry and in early mitosis Neddylation Antigen processing: Ubiquitination & Proteasome degradation
FBXO38	F-box protein 38
FBXW9	F-box and WD repeat domain containing 9	Association of TriC/CCT with target proteins during biosynthesis Neddylation Antigen processing: Ubiquitination & Proteasome degradation
FCF1	FCF1 rRNA-processing protein	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
FCGR3A	Fc gamma receptor IIIa	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell FCGR activation FCGR activation Regulation of actin dynamics for phagocytic cup formation Role of phospholipids in phagocytosis FCGR3A-mediated IL10 synthesis FCGR3A-mediated phagocytosis	Cetuximab Etanercept Human immunoglobulin G Gemtuzumab ozogamicin Alemtuzumab Alefacept Palivizumab Daclizumab Bevacizumab Catumaxomab Sarilumab Benralizumab Amivantamab	NK cell defects, including the following disease: CD16 deficiency Systemic lupus erythematosus
FCHO1	FCH and mu domain containing endocytic adaptor 1	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
FDX2	ferredoxin 2	Mitochondrial iron-sulfur cluster biogenesis Pregnenolone biosynthesis Endogenous sterols Electron transport from NADPH to Ferredoxin Defective CYP11A1 causes AICSR

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