OGT - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	Purine ribonucleoside monophosphate biosynthesis Signaling by ALK fusions and activated point mutants	Tetrahydrofolic acid Methotrexate Pemetrexed AICA ribonucleotide Guanosine-5'-Monophosphate 5-monophosphate-9-beta-D-ribofuranosyl xanthine Acid yellow 54 free acid N-[4-([(2-Amino-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid	AICA-ribosiduria; ATIC deficiency
ATL2	atlastin GTPase 2
ATL3	atlastin GTPase 3
ATP1B1	ATPase Na+/K+ transporting subunit beta 1	Basigin interactions Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Bisacodyl Tegoprazan
ATP1B3	ATPase Na+/K+ transporting subunit beta 3	Basigin interactions Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Bisacodyl Tegoprazan
ATP5F1A	ATP synthase F1 subunit alpha	Mitochondrial protein import Formation of ATP by chemiosmotic coupling Cristae formation Mitochondrial protein degradation	Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE Artenimol
ATP5F1B	ATP synthase F1 subunit beta	Mitochondrial protein import Mitochondrial protein import Formation of ATP by chemiosmotic coupling Transcriptional activation of mitochondrial biogenesis Cristae formation Mitochondrial protein degradation	Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE Phenethyl Isothiocyanate
ATP6AP1	ATPase H+ transporting accessory protein 1	Insulin receptor recycling RHOA GTPase cycle Transferrin endocytosis and recycling Ion channel transport	Tiludronic acid
ATXN10	ataxin 10			Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
ATXN2L	ataxin 2 like
B3GLCT	beta 3-glucosyltransferase	Defective B3GALTL causes PpS O-glycosylation of TSR domain-containing proteins
B4GAT1	beta-1,4-glucuronyltransferase 1	Keratan sulfate biosynthesis Defective LARGE causes MDDGA6 and MDDGB6 Matriglycan biosynthesis on DAG1
BAG1	BAG cochaperone 1	Regulation of HSF1-mediated heat shock response	(2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
BAIAP2	BAR/IMD domain containing adaptor protein 2	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs CDC42 GTPase cycle RAC1 GTPase cycle RAC3 GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
BCCIP	BRCA2 and CDKN1A interacting protein
BCLAF1	BCL2 associated transcription factor 1
BEND7	BEN domain containing 7
BIRC5	baculoviral IAP repeat containing 5	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Interleukin-4 and Interleukin-13 signaling TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain Mitotic Prometaphase Neddylation EML4 and NUDC in mitotic spindle formation	Reserpine Berberine LY2181308
BSG	basigin (Ok blood group)	Degradation of the extracellular matrix Basigin interactions Integrin cell surface interactions Proton-coupled monocarboxylate transport Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) Aspirin ADME
BTG3	BTG anti-proliferation factor 3

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