Search Results for: ATXN1

294 interactions involving ATXN1 - ataxin 1 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
CDIP1 cell death inducing p53 target 1
CDK6 cyclin dependent kinase 6
  • Oxidative Stress Induced Senescence
  • Senescence-Associated Secretory Phenotype (SASP)
  • Oncogene Induced Senescence
  • Cyclin D associated events in G1
  • Regulation of RUNX1 Expression and Activity
  • Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6
  • Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6
  • Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
  • Drug-mediated inhibition of CDK4/CDK6 activity
  • Alvocidib
  • (2S)-2-({6-[(3-Amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methyl-1-butanol
  • Fisetin
  • Palbociclib
  • Ribociclib
  • Abemaciclib
  • Trilaciclib
CDRT15P3 CDRT15 pseudogene 3
CFL1 cofilin 1
  • Platelet degranulation
  • Regulation of actin dynamics for phagocytic cup formation
  • EPHB-mediated forward signaling
  • Sema3A PAK dependent Axon repulsion
  • RHO GTPases Activate ROCKs
  • Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
  • Dodecyldimethylamine N-oxide
  • Copper
  • Artenimol
CHRNA7 cholinergic receptor nicotinic alpha 7 subunit
  • Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
  • Choline
  • Nicotine
  • Succinylcholine
  • Butabarbital
  • Butalbital
  • Talbutal
  • Pentobarbital
  • Methadone
  • Secobarbital
  • Metharbital
  • Dextromethorphan
  • Cisatracurium
  • Thiopental
  • Mecamylamine
  • Galantamine
  • Primidone
  • Methylphenobarbital
  • Ethanol
  • Amantadine
  • Phenobarbital
  • Tubocurarine
  • Varenicline
  • Amobarbital
  • Aprobarbital
  • Butobarbital
  • Heptabarbital
  • Hexobarbital
  • Barbital
  • Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione
  • Acetylcholine
  • Lobeline
  • GTS-21
  • RPI-78M
  • Epibatidine
  • Cytisine
  • Cannabidiol
  • Encenicline
  • Choline salicylate
  • Medical Cannabis
  • Nabiximols
CIC capicua transcriptional repressor
CIRBP cold inducible RNA binding protein
CLASRP CLK4 associating serine/arginine rich protein
CLCN2 chloride voltage-gated channel 2
  • Stimuli-sensing channels
  • Lubiprostone
  • Cobiprostone
  • Idiopathic generalied epilepsies (IGEs), including: Childhood absence epilepsy (CAE); Juvenile absence epilepsy (JAE); Juvenile myoclonic epilepsy (JME); Epilepsy with generalized tonic-clonic seizures alone
CLEC4F C-type lectin domain family 4 member F
COIL coilin
CPSF7 cleavage and polyadenylation specific factor 7
  • mRNA 3'-end processing
  • Processing of Capped Intron-Containing Pre-mRNA
  • RNA Polymerase II Transcription Termination
  • Processing of Intronless Pre-mRNAs
  • RHOBTB1 GTPase cycle
CREM cAMP responsive element modulator
CRIP2 cysteine rich protein 2
CRK CRK proto-oncogene, adaptor protein
  • ARMS-mediated activation
  • ARMS-mediated activation
  • Downstream signal transduction
  • Regulation of actin dynamics for phagocytic cup formation
  • p130Cas linkage to MAPK signaling for integrins
  • VEGFA-VEGFR2 Pathway
  • PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
  • MET activates RAP1 and RAC1
  • MET receptor recycling
  • Regulation of signaling by CBL
  • FCGR3A-mediated phagocytosis
CRX cone-rod homeobox
  • Leber congenital amaurosis (LCR)
  • Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
CRY2 cryptochrome circadian regulator 2
  • Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes
  • The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex
  • Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
  • Degradation of CRY and PER proteins
CST3 cystatin C
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • Neutrophil degranulation
  • Post-translational protein phosphorylation
  • Amyloid fiber formation
  • Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA)
CUTC cutC copper transporter
  • Ion transport by P-type ATPases
DAZ2 deleted in azoospermia 2

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