Search Results for: PTEN

770 interactions involving PTEN - phosphatase and tensin homolog found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
LTV1 LTV1 ribosome biogenesis factor
  • Major pathway of rRNA processing in the nucleolus and cytosol
MAGED2 MAGE family member D2
  • Platelet degranulation
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
  • Nephrin family interactions
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3
MAP2K3 mitogen-activated protein kinase kinase 3
  • Oxidative Stress Induced Senescence
  • activated TAK1 mediates p38 MAPK activation
  • Fostamatinib
  • Pimasertib
MAST1 microtubule associated serine/threonine kinase 1
  • Fostamatinib
MAST2 microtubule associated serine/threonine kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MATR3 matrin 3
  • Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
MCM2 minichromosome maintenance complex component 2
  • Activation of ATR in response to replication stress
  • Unwinding of DNA
  • Assembly of the pre-replicative complex
  • Assembly of the pre-replicative complex
  • Orc1 removal from chromatin
  • Activation of the pre-replicative complex
  • Switching of origins to a post-replicative state
  • Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence
MCM3 minichromosome maintenance complex component 3
  • Activation of ATR in response to replication stress
  • Unwinding of DNA
  • Assembly of the pre-replicative complex
  • Assembly of the pre-replicative complex
  • Orc1 removal from chromatin
  • Activation of the pre-replicative complex
  • Switching of origins to a post-replicative state
MCM5 minichromosome maintenance complex component 5
  • Activation of ATR in response to replication stress
  • Unwinding of DNA
  • Assembly of the pre-replicative complex
  • Assembly of the pre-replicative complex
  • Orc1 removal from chromatin
  • Activation of the pre-replicative complex
  • Switching of origins to a post-replicative state
  • Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence
MCRS1 microspherule protein 1
  • HATs acetylate histones
  • UCH proteinases
  • DNA Damage Recognition in GG-NER
  • Formation of WDR5-containing histone-modifying complexes
MDC1 mediator of DNA damage checkpoint 1
  • SUMOylation of DNA damage response and repair proteins
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • TP53 Regulates Transcription of DNA Repair Genes
  • G2/M DNA damage checkpoint
MDN1 midasin AAA ATPase 1
METTL26 methyltransferase like 26
MEX3C mex-3 RNA binding family member C
  • Antigen processing: Ubiquitination & Proteasome degradation
MKI67 marker of proliferation Ki-67
MME membrane metalloendopeptidase
  • Metabolism of Angiotensinogen to Angiotensins
  • Physiological factors
  • Neutrophil degranulation
  • Developmental Lineage of Mammary Gland Myoepithelial Cells
  • Candoxatril
  • Omapatrilat
  • N-[3-[(1-Aminoethyl)(Hydroxy)Phosphoryl]-2-(1,1'-Biphenyl-4-Ylmethyl)Propanoyl]Alanine
  • Phosphoramidon
  • N-(3-Phenyl-2-Sulfanylpropanoyl)Phenylalanylalanine
  • [2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala
  • Daglutril
  • 2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM
  • Thiorphan
  • Sacubitril
  • Candoxatrilat
MPRIP myosin phosphatase Rho interacting protein
  • Signaling by BRAF and RAF1 fusions

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