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TENT5A |
terminal nucleotidyltransferase 5A |
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TENT5B |
terminal nucleotidyltransferase 5B |
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TMX2 |
thioredoxin related transmembrane protein 2 |
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TOLLIP |
toll interacting protein |
- Neutrophil degranulation
- Interleukin-1 signaling
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TOMM20 |
translocase of outer mitochondrial membrane 20 |
- Mitochondrial protein import
- PINK1-PRKN Mediated Mitophagy
- Ub-specific processing proteases
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TOX4 |
TOX high mobility group box family member 4 |
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TP53I11 |
tumor protein p53 inducible protein 11 |
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TPRX1 |
tetrapeptide repeat homeobox 1 |
- Zygotic genome activation (ZGA)
- Zygotic genome activation (ZGA)
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TRAF2 |
TNF receptor associated factor 2 |
- Caspase activation via Death Receptors in the presence of ligand
- Regulation by c-FLIP
- RIPK1-mediated regulated necrosis
- CASP8 activity is inhibited
- TNFR1-induced proapoptotic signaling
- Regulation of TNFR1 signaling
- TNFR1-induced NF-kappa-B signaling pathway
- TNFR2 non-canonical NF-kB pathway
- Regulation of necroptotic cell death
- TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
- Ub-specific processing proteases
- Dimerization of procaspase-8
- TNF signaling
- TRAF6 mediated IRF7 activation
- TRAF6 mediated NF-kB activation
- TRAF6 mediated NF-kB activation
- Defective RIPK1-mediated regulated necrosis
- Regulation of NF-kappa B signaling
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TRIM32 |
tripartite motif containing 32 |
- Regulation of innate immune responses to cytosolic DNA
- Antigen processing: Ubiquitination & Proteasome degradation
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- Bardet-Biedl syndrome (BBS)
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TRIM38 |
tripartite motif containing 38 |
- Interferon gamma signaling
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TRIP6 |
thyroid hormone receptor interactor 6 |
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TSC1 |
TSC complex subunit 1 |
- Macroautophagy
- Inhibition of TSC complex formation by PKB
- Energy dependent regulation of mTOR by LKB1-AMPK
- TP53 Regulates Metabolic Genes
- TBC/RABGAPs
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- Lymphangioleiomyomatosis (LAM)
- Tuberous sclerosis complex (TSC); Bourneville-Pringle disease
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TTC19 |
tetratricopeptide repeat domain 19 |
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- Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
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U2AF2 |
U2 small nuclear RNA auxiliary factor 2 |
- Transport of Mature mRNA derived from an Intron-Containing Transcript
- mRNA Splicing - Major Pathway
- mRNA 3'-end processing
- RNA Polymerase II Transcription Termination
- Protein hydroxylation
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UBAP2L |
ubiquitin associated protein 2 like |
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UBE2E3 |
ubiquitin conjugating enzyme E2 E3 |
- Synthesis of active ubiquitin: roles of E1 and E2 enzymes
- Antigen processing: Ubiquitination & Proteasome degradation
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UBE2I |
ubiquitin conjugating enzyme E2 I |
- Meiotic synapsis
- Vitamin D (calciferol) metabolism
- SUMO is transferred from E1 to E2 (UBE2I, UBC9)
- SUMO is transferred from E1 to E2 (UBE2I, UBC9)
- SUMOylation of DNA damage response and repair proteins
- SUMOylation of transcription factors
- SUMOylation of transcription factors
- SUMOylation of ubiquitinylation proteins
- SUMOylation of transcription cofactors
- SUMOylation of transcription cofactors
- SUMOylation of SUMOylation proteins
- SUMOylation of intracellular receptors
- SUMOylation of intracellular receptors
- SUMOylation of chromatin organization proteins
- SUMOylation of chromatin organization proteins
- SUMOylation of RNA binding proteins
- SUMOylation of DNA replication proteins
- SUMOylation of DNA replication proteins
- SUMOylation of DNA methylation proteins
- SUMOylation of DNA methylation proteins
- SUMOylation of immune response proteins
- Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
- Processing of DNA double-strand break ends
- Formation of Incision Complex in GG-NER
- Negative regulation of activity of TFAP2 (AP-2) family transcription factors
- Negative regulation of activity of TFAP2 (AP-2) family transcription factors
- Postmitotic nuclear pore complex (NPC) reformation
- Maturation of nucleoprotein
- Maturation of nucleoprotein
- SARS-CoV-1 targets host intracellular signalling and regulatory pathways
- SUMOylation of nuclear envelope proteins
- PKR-mediated signaling
- Regulation of endogenous retroelements by KRAB-ZFP proteins
- Transcriptional and post-translational regulation of MITF-M expression and activity
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UBQLN4 |
ubiquilin 4 |
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UHRF2 |
ubiquitin like with PHD and ring finger domains 2 |
- SUMOylation of transcription cofactors
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