ATXN1 - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
RBPMS	RNA binding protein, mRNA processing factor
RCC1L	RCC1 like	rRNA modification in the mitochondrion Mitochondrial mRNA modification
RCN1	reticulocalbin 1	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
REL	REL proto-oncogene, NF-kB subunit	Activation of NF-kappaB in B cells		Hodgkin lymphoma
RHOXF2	Rhox homeobox family member 2
RNF10	ring finger protein 10
RNF31	ring finger protein 31	TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NF-kappa-B signaling pathway
RNF4	ring finger protein 4	Processing of DNA double-strand break ends Antigen processing: Ubiquitination & Proteasome degradation
RPL19	ribosomal protein L19	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	(S)-3-phenyllactic acid Anisomycin Puromycin
SAR1A	secretion associated Ras related GTPase 1A
SEMA4G	semaphorin 4G
SETD2	SET domain containing 2, histone lysine methyltransferase	PKMTs methylate histone lysines
SETD6	SET domain containing 6, protein lysine methyltransferase	PKMTs methylate histone lysines
SF1	splicing factor 1	mRNA Splicing - Major Pathway	Artenimol
SGMS1	sphingomyelin synthase 1	Sphingolipid de novo biosynthesis
SIX5	SIX homeobox 5			Contiguous gene deletion syndrome involving EYA1, including: Oto-facio-cervical syndrome (OFC); Branchiootic syndrome 1 (BOS1); Branchio-oto-renal syndrome (BOR)
SLC25A51	solute carrier family 25 member 51	Nicotinate metabolism
SLC4A2	solute carrier family 4 member 2	Bicarbonate transporters
SLC51A	solute carrier family 51 member A	Recycling of bile acids and salts
SLC6A13	solute carrier family 6 member 13	SLC-mediated transport of neurotransmitters Reuptake of GABA	Guvacine

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