Search Results for: APP

2116 interactions involving APP - amyloid beta precursor protein found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
DLGAP5 DLG associated protein 5
  • NOTCH3 Intracellular Domain Regulates Transcription
DLK2 delta like non-canonical Notch ligand 2
DMAC1 distal membrane arm assembly component 1
  • Complex I biogenesis
DMD dystrophin
  • Non-integrin membrane-ECM interactions
  • Striated Muscle Contraction
  • Formation of the dystrophin-glycoprotein complex (DGC)
  • Formation of the dystrophin-glycoprotein complex (DGC)
  • Golodirsen
  • Dilated cardiomyopathy (DCM)
  • Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)
  • Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM)
DMKN dermokine
  • Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
DMTN dematin actin binding protein
  • Miscellaneous transport and binding events
DNAAF2 dynein axonemal assembly factor 2
  • Primary ciliary dyskinesia, including: Primary ciliary dyskinesia; Kartagener syndrome
DNAH14 dynein axonemal heavy chain 14
DNAJB1 DnaJ heat shock protein family (Hsp40) member B1
  • Regulation of HSF1-mediated heat shock response
  • HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
  • Attenuation phase
  • HSF1-dependent transactivation
  • MAPK6/MAPK4 signaling
DNAJB14 DnaJ heat shock protein family (Hsp40) member B14
DNAJB6 DnaJ heat shock protein family (Hsp40) member B6
  • Regulation of HSF1-mediated heat shock response
DNAJB7 DnaJ heat shock protein family (Hsp40) member B7
DNAJC12 DnaJ heat shock protein family (Hsp40) member C12
DNAJC19 DnaJ heat shock protein family (Hsp40) member C19
  • Mitochondrial protein import
  • 3-Methylglutaconic aciduria (MGCA)
DNAJC4 DnaJ heat shock protein family (Hsp40) member C4
DNAJC8 DnaJ heat shock protein family (Hsp40) member C8
  • mRNA Splicing - Major Pathway
DNALI1 dynein axonemal light intermediate chain 1
DNM2 dynamin 2
  • Toll Like Receptor 4 (TLR4) Cascade
  • Retrograde neurotrophin signalling
  • Gap junction degradation
  • Formation of annular gap junctions
  • NOSTRIN mediated eNOS trafficking
  • MHC class II antigen presentation
  • Lysosome Vesicle Biogenesis
  • Golgi Associated Vesicle Biogenesis
  • Recycling pathway of L1
  • Clathrin-mediated endocytosis
  • NGF-stimulated transcription
  • Degradation of CDH1
  • Centronuclear myopathy
  • Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
DPCD deleted in primary ciliary dyskinesia homolog (mouse)
DPP3 dipeptidyl peptidase 3
  • Neddylation
  • KEAP1-NFE2L2 pathway

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