OGT - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
PACSIN3	protein kinase C and casein kinase substrate in neurons 3	Clathrin-mediated endocytosis
PAIP1	poly(A) binding protein interacting protein 1	Deadenylation of mRNA Deadenylation of mRNA M-decay: degradation of maternal mRNAs by maternally stored factors Z-decay: degradation of maternal mRNAs by zygotically expressed factors
PAK2	p21 (RAC1) activated kinase 2	Nef and signal transduction Generation of second messenger molecules Regulation of PAK-2p34 activity by PS-GAP/RHG10 Regulation of activated PAK-2p34 by proteasome mediated degradation Stimulation of the cell death response by PAK-2p34 FCERI mediated MAPK activation FCERI mediated MAPK activation CD28 dependent Vav1 pathway Ephrin signaling Sema3A PAK dependent Axon repulsion Activation of RAC1 VEGFA-VEGFR2 Pathway Smooth Muscle Contraction VEGFR2 mediated vascular permeability CD209 (DC-SIGN) signaling RHO GTPases activate PAKs RHO GTPases activate PAKs MAPK6/MAPK4 signaling Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOH GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RHOU GTPase cycle RAC3 GTPase cycle RHOV GTPase cycle	Fostamatinib
PALS2	protein associated with LIN7 2, MAGUK p55 family member
PARD6B	par-6 family cell polarity regulator beta	Tight junction interactions RHOV GTPase cycle
PARG	poly(ADP-ribose) glycohydrolase	POLB-Dependent Long Patch Base Excision Repair
PARP1	poly(ADP-ribose) polymerase 1	POLB-Dependent Long Patch Base Excision Repair vRNA Synthesis Downregulation of SMAD2/3:SMAD4 transcriptional activity SUMOylation of DNA damage response and repair proteins HDR through MMEJ (alt-NHEJ) DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER Dual Incision in GG-NER	Theophylline Zinc Carba-nicotinamide-adenine-dinucleotide NU1025 Nicotinamide 2-{3-[4-(4-Fluorophenyl)-3,6-Dihydro-1(2h)-Pyridinyl]Propyl}-8-Methyl-4(3h)-Quinazolinone 3-Methoxybenzamide 2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide 3,4-Dihydro-5-Methyl-Isoquinolinone 2-(3'-Methoxyphenyl) Benzimidazole-4-Carboxamide 6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE Veliparib A-620223 5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE Olaparib Talazoparib Niraparib Rucaparib Iniparib Zinc acetate Zinc chloride Zinc sulfate, unspecified form
PARVA	parvin alpha	Localization of the PINCH-ILK-PARVIN complex to focal adhesions Cell-extracellular matrix interactions Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
PCBP1	poly(rC) binding protein 1	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
PCBP2	poly(rC) binding protein 2	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Negative regulators of DDX58/IFIH1 signaling SARS-CoV-1 activates/modulates innate immune responses
PCGF2	polycomb group ring finger 2	SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins Activation of anterior HOX genes in hindbrain development during early embryogenesis Transcriptional Regulation by E2F6
PCGF6	polycomb group ring finger 6	Transcriptional Regulation by E2F6
PCYOX1	prenylcysteine oxidase 1
PDCD2L	programmed cell death 2 like
PDCD4	programmed cell death 4	Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
PDCD7	programmed cell death 7	mRNA Splicing - Minor Pathway
PDHX	pyruvate dehydrogenase complex component X	Regulation of pyruvate dehydrogenase (PDH) complex Signaling by Retinoic Acid PDH complex synthesizes acetyl-CoA from PYR		Pyruvate dehydrogenase complex deficiency; X-linked Leigh syndrome
PDIA3	protein disulfide isomerase family A member 3	ER-Phagosome pathway ER-Phagosome pathway Calnexin/calreticulin cycle Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
PDIA5	protein disulfide isomerase family A member 5	XBP1(S) activates chaperone genes
PDIA6	protein disulfide isomerase family A member 6	XBP1(S) activates chaperone genes Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation

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