ZYX - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Associated Diseases Hide
RABEPK	Rab9 effector protein with kelch motifs	Retrograde transport at the Trans-Golgi-Network
RGS2	regulator of G protein signaling 2	G alpha (q) signalling events
RPH3AL	rabphilin 3A like (without C2 domains)
RTN4IP1	reticulon 4 interacting protein 1
SIAH1	siah E3 ubiquitin protein ligase 1	Netrin-1 signaling Amyloid fiber formation Antigen processing: Ubiquitination & Proteasome degradation
SREBF2	sterol regulatory element binding transcription factor 2	Regulation of cholesterol biosynthesis by SREBP (SREBF) Regulation of cholesterol biosynthesis by SREBP (SREBF) Cholesterol biosynthesis PPARA activates gene expression Activation of gene expression by SREBF (SREBP) Activation of gene expression by SREBF (SREBP) Transcriptional regulation of white adipocyte differentiation EGR2 and SOX10-mediated initiation of Schwann cell myelination
TES	testin LIM domain protein
TUFT1	tuftelin 1
VASP	vasodilator stimulated phosphoprotein	Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors Cell-extracellular matrix interactions
VAV1	vav guanine nucleotide exchange factor 1	GPVI-mediated activation cascade GPVI-mediated activation cascade PIP3 activates AKT signaling Signaling by SCF-KIT NRAGE signals death through JNK Regulation of actin dynamics for phagocytic cup formation Constitutive Signaling by Aberrant PI3K in Cancer FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization CD28 dependent Vav1 pathway G alpha (12/13) signalling events VEGFA-VEGFR2 Pathway VEGFA-VEGFR2 Pathway Interleukin-3, Interleukin-5 and GM-CSF signaling VEGFR2 mediated vascular permeability PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling RHOA GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOG GTPase cycle Erythropoietin activates RAS Erythropoietin activates RAS Regulation of signaling by CBL FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis Potential therapeutics for SARS Azathioprine ADME Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
VAV3	vav guanine nucleotide exchange factor 3	GPVI-mediated activation cascade GPVI-mediated activation cascade NRAGE signals death through JNK Regulation of actin dynamics for phagocytic cup formation DAP12 signaling FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization EPH-ephrin mediated repulsion of cells G alpha (12/13) signalling events VEGFA-VEGFR2 Pathway VEGFA-VEGFR2 Pathway VEGFR2 mediated vascular permeability RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOG GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis Azathioprine ADME
WNK1	WNK lysine deficient protein kinase 1	Stimuli-sensing channels	Hyperkalemic distal renal tubular acidosis (RTA type 4), including the following two diseases: Pseudohypoaldosteronism type I (PHA1); Pseudohypoaldosteronism type II (Gordon's syndrome)
YPEL3	yippee like 3
ZHX1	zinc fingers and homeoboxes 1
ZNF384	zinc finger protein 384
ZNF512B	zinc finger protein 512B	RHOV GTPase cycle

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