Search Results for: USP2

178 interactions involving USP2 - ubiquitin specific peptidase 2 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
CARD9 caspase recruitment domain family member 9
  • NOD1/2 Signaling Pathway
  • CLEC7A (Dectin-1) signaling
  • Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
CBLC Cbl proto-oncogene C
CCDC136 coiled-coil domain containing 136
CCDC57 coiled-coil domain containing 57
CCDC85B coiled-coil domain containing 85B
CCDC88B coiled-coil and HOOK domain protein 88B
CDC34 cell division cycle 34, ubiquitin conjugating enzyme
  • Downstream TCR signaling
  • FCERI mediated NF-kB activation
  • CLEC7A (Dectin-1) signaling
  • Synthesis of active ubiquitin: roles of E1 and E2 enzymes
  • Antigen processing: Ubiquitination & Proteasome degradation
CEP63 centrosomal protein 63
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • AURKA Activation by TPX2
CEP70 centrosomal protein 70
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • AURKA Activation by TPX2
CRACR2A calcium release activated channel regulator 2A
  • Neutrophil degranulation
CRACR2B calcium release activated channel regulator 2B
CRY1 cryptochrome circadian regulator 1
  • Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes
  • The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex
  • Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
  • Degradation of CRY and PER proteins
DCAF1 DDB1 and CUL4 associated factor 1
  • Antigen processing: Ubiquitination & Proteasome degradation
DDI1 DDI proteasomal shuttling factor 1
DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit
  • Amino acids regulate mTORC1
DISC1 DISC1 scaffold protein
DSCR4 Down syndrome critical region 4
DTX3 deltex E3 ubiquitin ligase 3
DUSP21 dual specificity phosphatase 21
DYDC1 DPY30 domain containing 1

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