SMARCB1 - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
CXCL11	C-X-C motif chemokine ligand 11	Chemokine receptors bind chemokines G alpha (i) signalling events
CYB5D2	cytochrome b5 domain containing 2
DNAJA3	DnaJ heat shock protein family (Hsp40) member A3
DPH6	diphthamine biosynthesis 6	Synthesis of diphthamide-EEF2
EZH2	enhancer of zeste 2 polycomb repressive complex 2 subunit	PRC2 methylates histones and DNA Oxidative Stress Induced Senescence PKMTs methylate histone lysines Activation of anterior HOX genes in hindbrain development during early embryogenesis Regulation of PTEN gene transcription Regulation of PTEN gene transcription Transcriptional Regulation by E2F6 HCMV Early Events Defective pyroptosis Negative Regulation of CDH1 Gene Transcription Regulation of PD-L1(CD274) transcription	Tazemetostat CPI-1205
FAM90A1	family with sequence similarity 90 member A1
FAM9B	family with sequence similarity 9 member B
FUS	FUS RNA binding protein	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA		Myxoid liposarcoma Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GADD45G	growth arrest and DNA damage inducible gamma
GATA1	GATA binding protein 1	RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function RUNX1 regulates transcription of genes involved in differentiation of HSCs Factors involved in megakaryocyte development and platelet production		Congenital dyserythropoietic anemias (CDAs) Thrombocytopenia (THC); Familial platelet disorder with associated myeloid malignancy (FPDMM)
GFAP	glial fibrillary acidic protein	Nuclear signaling by ERBB4 Chaperone Mediated Autophagy		Alexander disease
GOLGA2	golgin A2	Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	EGFR downregulation Lysosome Vesicle Biogenesis Ub-specific processing proteases Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell RHOU GTPase cycle Endosomal Sorting Complex Required For Transport (ESCRT) Inhibition of membrane repair Prevention of phagosomal-lysosomal fusion RHOBTB3 ATPase cycle	Citric acid
HNRNPM	heterogeneous nuclear ribonucleoprotein M	FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
HOMEZ	homeobox and leucine zipper encoding
HOOK2	hook microtubule tethering protein 2
HSF2BP	heat shock transcription factor 2 binding protein
HSFY1	heat shock transcription factor Y-linked 1
IHO1	interactor of HORMAD1 1
IKZF3	IKAROS family zinc finger 3

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