OGT - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
ALDH4A1	aldehyde dehydrogenase 4 family member A1	Glyoxylate metabolism and glycine degradation Proline catabolism	NADH	Hyperprolinemia (HP)
ALDH5A1	aldehyde dehydrogenase 5 family member A1	Degradation of GABA	Succinic acid NADH Valproic acid Chlormerodrin	Succinic semialdehyde dehydrogenase (SSADH) deficiency; 4-Hydroxybutyric aciduria (4-HBA)
ALDH6A1	aldehyde dehydrogenase 6 family member A1	Branched-chain amino acid catabolism	NADH
ALDH7A1	aldehyde dehydrogenase 7 family member A1	Choline catabolism Lysine catabolism	NADH Artenimol
ALDOA	aldolase, fructose-bisphosphate A	Platelet degranulation Neutrophil degranulation Glycolysis Gluconeogenesis	Zinc 1,6-Fructose Diphosphate (Linear Form) Dihydroxyacetone phosphate 1,6-DI-O-PHOSPHONO-D-MANNITOL N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
ALKBH5	alkB homolog 5, RNA demethylase	Reversal of alkylation damage by DNA dioxygenases
ANAPC7	anaphase promoting complex subunit 7	Inactivation of APC/C via direct inhibition of the APC/C complex APC/C:Cdc20 mediated degradation of Cyclin B Autodegradation of Cdh1 by Cdh1:APC/C APC/C:Cdc20 mediated degradation of Securin APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Cdc20:Phospho-APC/C mediated degradation of Cyclin A Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase Regulation of APC/C activators between G1/S and early anaphase APC/C:Cdc20 mediated degradation of mitotic proteins Phosphorylation of the APC/C APC-Cdc20 mediated degradation of Nek2A Separation of Sister Chromatids Senescence-Associated Secretory Phenotype (SASP) Assembly of the pre-replicative complex CDK-mediated phosphorylation and removal of Cdc6 Transcriptional Regulation by VENTX Aberrant regulation of mitotic exit in cancer due to RB1 defects Antigen processing: Ubiquitination & Proteasome degradation
ANXA11	annexin A11
ANXA6	annexin A6	Smooth Muscle Contraction
ANXA7	annexin A7
API5	apoptosis inhibitor 5
APMAP	adipocyte plasma membrane associated protein
APOH	apolipoprotein H	Platelet degranulation	LJP 1082 Copper
ARHGAP1	Rho GTPase activating protein 1	RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle RND2 GTPase cycle
ARHGAP19	Rho GTPase activating protein 19	RHOA GTPase cycle
ARIH2	ariadne RBR E3 ubiquitin protein ligase 2	Antigen processing: Ubiquitination & Proteasome degradation
ARMC6	armadillo repeat containing 6
ASCC1	activating signal cointegrator 1 complex subunit 1	ALKBH3 mediated reversal of alkylation damage
ASPH	aspartate beta-hydroxylase	Stimuli-sensing channels Ion homeostasis Protein hydroxylation	Aspartic acid
ATAD3A	ATPase family AAA domain containing 3A

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