Search Results for: BRIP1

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
HPN hepsin
  • MET Receptor Activation
  • Signaling by MST1
  • Bentiromide
  • Benzylsulfonic acid
  • CRA_1144
  • 6-Chloro-2-(2-Hydroxy-Biphenyl-3-Yl)-1h-Indole-5-Carboxamidine
HSD17B14 hydroxysteroid 17-beta dehydrogenase 14
  • Estrogen biosynthesis
MRPS23 mitochondrial ribosomal protein S23
  • Mitochondrial translation initiation
  • Mitochondrial translation elongation
  • Mitochondrial translation elongation
  • Mitochondrial translation termination
  • Mitochondrial ribosome-associated quality control
PATZ1 POZ/BTB and AT hook containing zinc finger 1
PECAM1 platelet and endothelial cell adhesion molecule 1
  • Platelet degranulation
  • Cell surface interactions at the vascular wall
  • PECAM1 interactions
  • Integrin cell surface interactions
  • Platelet sensitization by LDL
  • Neutrophil degranulation
  • High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
RPA1 replication protein A1
  • Translesion synthesis by REV1
  • Recognition of DNA damage by PCNA-containing replication complex
  • Translesion Synthesis by POLH
  • Removal of the Flap Intermediate from the C-strand
  • Activation of ATR in response to replication stress
  • SUMOylation of DNA damage response and repair proteins
  • Regulation of HSF1-mediated heat shock response
  • HSF1 activation
  • Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
  • Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
  • Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
  • PCNA-Dependent Long Patch Base Excision Repair
  • Translesion synthesis by POLK
  • Translesion synthesis by POLI
  • Termination of translesion DNA synthesis
  • HDR through Single Strand Annealing (SSA)
  • HDR through Homologous Recombination (HRR)
  • Processing of DNA double-strand break ends
  • Presynaptic phase of homologous DNA pairing and strand exchange
  • Formation of Incision Complex in GG-NER
  • Gap-filling DNA repair synthesis and ligation in GG-NER
  • Dual Incision in GG-NER
  • Dual incision in TC-NER
  • Gap-filling DNA repair synthesis and ligation in TC-NER
  • Fanconi Anemia Pathway
  • Regulation of TP53 Activity through Phosphorylation
  • Activation of the pre-replicative complex
  • Removal of the Flap Intermediate
  • G2/M DNA damage checkpoint
  • Meiotic recombination
  • Impaired BRCA2 binding to RAD51
SIRT1 sirtuin 1
  • Regulation of HSF1-mediated heat shock response
  • SIRT1 negatively regulates rRNA expression
  • SIRT1 negatively regulates rRNA expression
  • Regulation of FOXO transcriptional activity by acetylation
  • Regulation of FOXO transcriptional activity by acetylation
  • Heme signaling
  • Negative Regulation of CDH1 Gene Transcription
  • MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
  • Regulation of MITF-M dependent genes involved in metabolism
  • Transcriptional and post-translational regulation of MITF-M expression and activity
  • Expression of BMAL (ARNTL), CLOCK, and NPAS2
  • Resveratrol
  • Selisistat
  • Cambinol
TOPBP1 DNA topoisomerase II binding protein 1
  • HDR through Single Strand Annealing (SSA)
  • Processing of DNA double-strand break ends
  • Presynaptic phase of homologous DNA pairing and strand exchange
  • Regulation of TP53 Activity through Phosphorylation
  • G2/M DNA damage checkpoint
  • Impaired BRCA2 binding to RAD51

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