Search Results for: APP

2116 interactions involving APP - amyloid beta precursor protein found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
ACKR2 atypical chemokine receptor 2
  • Chemokine receptors bind chemokines
ACLY ATP citrate lyase
  • ChREBP activates metabolic gene expression
  • Neutrophil degranulation
  • Fatty acyl-CoA biosynthesis
  • Bempedoic acid
ACO1 aconitase 1
  • NADPH regeneration
  • Iron uptake and transport
ACO2 aconitase 2
  • Mitochondrial protein import
  • Citric acid cycle (TCA cycle)
  • Mitochondrial protein degradation
  • Maturation of TCA enzymes and regulation of TCA cycle
  • Isocitric Acid
  • 4-Hydroxy-Aconitate Ion
  • Alpha-Methylisocitric Acid
  • Aconitate Ion
  • Tricarballylic acid
ACSBG1 acyl-CoA synthetase bubblegum family member 1
  • Synthesis of very long-chain fatty acyl-CoAs
  • 2-(6-HYDROXY-1,3-BENZOTHIAZOL-2-YL)-1,3-THIAZOL-4(5H)-ONE
ACSL3 acyl-CoA synthetase long chain family member 3
  • Intracellular metabolism of fatty acids regulates insulin secretion
  • Synthesis of very long-chain fatty acyl-CoAs
ACSL4 acyl-CoA synthetase long chain family member 4
  • Intracellular metabolism of fatty acids regulates insulin secretion
  • Synthesis of very long-chain fatty acyl-CoAs
  • Icosapent
  • Troglitazone
  • Rosiglitazone
  • Non-syndromic X-linked mental retardation
ACTL6B actin like 6B
  • RMTs methylate histone arginines
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
ACTL7A actin like 7A
ACTL7B actin like 7B
ACTR1B actin related protein 1B
  • MHC class II antigen presentation
  • Neutrophil degranulation
ACY1 aminoacylase 1
  • Aflatoxin activation and detoxification
  • Defective ACY1 causes encephalopathy
  • Paracetamol ADME
  • Aspartic acid
  • Acetylcysteine
  • Copper
ACYP1 acylphosphatase 1
ADAD2 adenosine deaminase domain containing 2
ADAM22 ADAM metallopeptidase domain 22
  • LGI-ADAM interactions
ADAP2 ArfGAP with dual PH domains 2
ADARB1 adenosine deaminase RNA specific B1
  • C6 deamination of adenosine
  • Formation of editosomes by ADAR proteins
ADAT2 adenosine deaminase tRNA specific 2
  • tRNA modification in the nucleus and cytosol
ADD2 adducin 2
  • Miscellaneous transport and binding events
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
  • RA biosynthesis pathway
  • Ethanol oxidation
  • NADH
  • Cyclohexylformamide

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