OGT - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
NDUFV1	NADH:ubiquinone oxidoreductase core subunit V1	Respiratory electron transport Complex I biogenesis Mitochondrial protein degradation	NADH	Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
NELFCD	negative elongation factor complex member C/D	Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
NHERF1	NHERF family PDZ scaffold protein 1			Nephrolithiasis/osteoporosis, hypophosphatemic
NISCH	nischarin	RAC1 GTPase cycle RND3 GTPase cycle RND2 GTPase cycle	Tizanidine Agmatine Moxonidine Tepotinib
NKAP	NFKB activating protein	mRNA Splicing - Major Pathway
NOC4L	nucleolar complex associated 4 homolog	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
NOLC1	nucleolar and coiled-body phosphoprotein 1		Doxorubicin
NOM1	nucleolar protein with MIF4G domain 1
NONO	non-POU domain containing octamer binding
NOP53	NOP53 ribosome biogenesis factor
NOP58	NOP58 ribonucleoprotein	SUMOylation of RNA binding proteins rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
NPM1	nucleophosmin 1	Nuclear import of Rev protein Nuclear import of Rev protein SUMOylation of transcription cofactors Deposition of new CENPA-containing nucleosomes at the centromere TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation SARS-CoV-1-host interactions ALK mutants bind TKIs Signaling by ALK fusions and activated point mutants Nuclear events stimulated by ALK signaling in cancer PKR-mediated signaling	Artenimol
NSMCE4A	NSE4A component of SMC5/6 complex	SUMOylation of DNA damage response and repair proteins
NSUN5	NOP2/Sun RNA methyltransferase 5
NSUN6	NOP2/Sun RNA methyltransferase 6	tRNA modification in the nucleus and cytosol
NT5DC1	5'-nucleotidase domain containing 1
NUDC	nuclear distribution C, dynein complex regulator	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation RND2 GTPase cycle	Phenethyl Isothiocyanate
NUF2	NUF2 component of NDC80 kinetochore complex	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
NUFIP1	nuclear FMR1 interacting protein 1
NUFIP2	nuclear FMR1 interacting protein 2

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