PTEN - Wiki-MPM

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	SMARCA4	SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4	Interleukin-7 signaling Formation of the beta-catenin:TCF transactivating complex RMTs methylate histone arginines Chromatin modifying enzymes RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known EGR2 and SOX10-mediated initiation of Schwann cell myelination EGR2 and SOX10-mediated initiation of Schwann cell myelination Negative Regulation of CDH1 Gene Transcription Regulation of MITF-M-dependent genes involved in pigmentation Regulation of MITF-M-dependent genes involved in pigmentation Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Formation of the canonical BAF (cBAF) complex Formation of the polybromo-BAF (pBAF) complex Formation of the embryonic stem cell BAF (esBAF) complex Formation of the non-canonical BAF (ncBAF) complex Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Novel	SMARCA5	SNF2 related chromatin remodeling ATPase 5	NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Deposition of new CENPA-containing nucleosomes at the centromere	Beta-D-Glucose 4-Deoxy-Alpha-D-Glucose
Novel	SMC2	structural maintenance of chromosomes 2	Condensation of Prophase Chromosomes Condensation of Prometaphase Chromosomes Condensation of Prometaphase Chromosomes
Novel	SMC4	structural maintenance of chromosomes 4	Condensation of Prophase Chromosomes Condensation of Prometaphase Chromosomes Condensation of Prometaphase Chromosomes
Novel	SMCHD1	structural maintenance of chromosomes flexible hinge domain containing 1
Novel	SMURF1	SMAD specific E3 ubiquitin protein ligase 1	Signaling by BMP Downregulation of TGF-beta receptor signaling TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Asymmetric localization of PCP proteins Hedgehog 'on' state Hedgehog 'on' state Regulation of RUNX2 expression and activity Regulation of RUNX2 expression and activity Regulation of RUNX3 expression and activity Antigen processing: Ubiquitination & Proteasome degradation
Novel	SNAI1	snail family transcriptional repressor 1	Regulation of PTEN gene transcription Regulation of PTEN gene transcription Epithelial-Mesenchymal Transition (EMT) during gastrulation Regulation of CDH11 gene transcription Negative Regulation of CDH1 Gene Transcription
Novel	SNRNP200	small nuclear ribonucleoprotein U5 subunit 200	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway		Retinitis pigmentosa (RP)
Novel	SNRPA1	small nuclear ribonucleoprotein polypeptide A'	mRNA Splicing - Major Pathway Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Novel	SNRPB2	small nuclear ribonucleoprotein polypeptide B2	mRNA Splicing - Major Pathway
Novel	SNRPD1	small nuclear ribonucleoprotein D1 polypeptide	snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway SARS-CoV-2 modulates host translation machinery
Novel	SNTB2	syntrophin beta 2	Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Novel	SNX27	sorting nexin 27
Novel	SPOP	speckle type BTB/POZ protein	Hedgehog 'on' state SPOP-mediated proteasomal degradation of PD-L1(CD274)
Novel	SPTAN1	spectrin alpha, non-erythrocytic 1	Caspase-mediated cleavage of cytoskeletal proteins Nephrin family interactions NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade Neutrophil degranulation COPI-mediated anterograde transport RHOU GTPase cycle RHOV GTPase cycle Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea		Early infantile epileptic encephalopathy; Ohtahara syndrome
Novel	SPTBN1	spectrin beta, non-erythrocytic 1	Nephrin family interactions NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade COPI-mediated anterograde transport RHOU GTPase cycle RHOV GTPase cycle Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins	Calcium 1D-myo-inositol 1,4,5-trisphosphate
Novel	SRP14	signal recognition particle 14	SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Neutrophil degranulation	Artenimol
Novel	SSB	small RNA binding exonuclease protection factor La	RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation
Novel	SSR4	signal sequence receptor subunit 4	SRP-dependent cotranslational protein targeting to membrane
Novel	SSRP1	structure specific recognition protein 1	Formation of RNA Pol II elongation complex Formation of HIV elongation complex in the absence of HIV Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Transcription Elongation

Search Results for: PTEN