EGFR - Wiki-MPM

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	RNF115	ring finger protein 115	Antigen processing: Ubiquitination & Proteasome degradation
Novel	RNF126	ring finger protein 126	Antigen processing: Ubiquitination & Proteasome degradation
Novel	RNF128	ring finger protein 128	Ub-specific processing proteases Ovarian tumor domain proteases
Novel	RNF130	ring finger protein 130	Antigen processing: Ubiquitination & Proteasome degradation
Novel	RNF144A	ring finger protein 144A	E3 ubiquitin ligases ubiquitinate target proteins
Novel	RNF167	ring finger protein 167
Novel	RRAD	RRAD, Ras related glycolysis inhibitor and calcium channel regulator	NGF-stimulated transcription
Novel	RUSC2	RUN and SH3 domain containing 2
Novel	S100A4	S100 calcium binding protein A4		Trifluoperazine Copper
Novel	S100A7	S100 calcium binding protein A7	Neutrophil degranulation Metal sequestration by antimicrobial proteins	Ibuprofen Zinc 8-anilinonaphthalene-1-sulfonic acid Dexibuprofen Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Novel	S100A9	S100 calcium binding protein A9	ER-Phagosome pathway MyD88:MAL(TIRAP) cascade initiated on plasma membrane MyD88 deficiency (TLR2/4) IRAK4 deficiency (TLR2/4) RHO GTPases Activate NADPH Oxidases Regulation of TLR by endogenous ligand Neutrophil degranulation Metal sequestration by antimicrobial proteins	Calcium Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Novel	SCAMP1	secretory carrier membrane protein 1	Neutrophil degranulation
Novel	SCAMP3	secretory carrier membrane protein 3
Novel	SEC13	SEC13 homolog, nuclear pore and COPII component	ISG15 antiviral mechanism Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly COPII-mediated vesicle transport MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) RHO GTPases Activate Formins tRNA processing in the nucleus Mitotic Prometaphase HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation Amino acids regulate mTORC1 EML4 and NUDC in mitotic spindle formation SARS-CoV-2 activates/modulates innate and adaptive immune responses Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Novel	SELENOP	selenoprotein P	Platelet degranulation	Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Novel	SFN	stratifin	Activation of BAD and translocation to mitochondria Translocation of SLC2A4 (GLUT4) to the plasma membrane RHO GTPases activate PKNs TP53 Regulates Metabolic Genes TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex Regulation of localization of FOXO transcription factors SARS-CoV-1 targets host intracellular signalling and regulatory pathways SARS-CoV-2 targets host intracellular signalling and regulatory pathways
Novel	SGSM2	small G protein signaling modulator 2
Novel	SH2B1	SH2B adaptor protein 1	Factors involved in megakaryocyte development and platelet production
Novel	SH2B2	SH2B adaptor protein 2	Regulation of KIT signaling Factors involved in megakaryocyte development and platelet production
Novel	SH2B3	SH2B adaptor protein 3	Regulation of KIT signaling Negative regulation of FLT3 Factors involved in megakaryocyte development and platelet production	Pazopanib	Type I diabetes mellitus

Search Results for: EGFR