UBC - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
FLOT2	flotillin 2	RIPK1-mediated regulated necrosis Regulation of necroptotic cell death Synaptic adhesion-like molecules RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle RND3 GTPase cycle RND1 GTPase cycle
FOXF1	forkhead box F1	Formation of lateral plate mesoderm Regulation of CDH11 gene transcription		Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV)
FSHR	follicle stimulating hormone receptor	Hormone ligand-binding receptors G alpha (s) signalling events	Menotropins Follitropin Urofollitropin Choriogonadotropin alfa Suramin Corifollitropin alfa	Ovarian hyperstimulation syndrome (OHSS) Premature ovarian failure 46,XX disorders of sex development (Disorders of gonadal development), including: Ovotesticular DSD; Testicular DSD; Ovarian dysgenesis
FTL	ferritin light chain	Scavenging by Class A Receptors Golgi Associated Vesicle Biogenesis Neutrophil degranulation Iron uptake and transport	Iron Dextran Protoporphyrin Ferric pyrophosphate Sodium ferric gluconate complex Ferric pyrophosphate citrate	Neurodegeneration with brain iron accumulation (NBIA); Hallervorden-Spatz syndrome; Neuroferritinopathy; Aceruloplasminemia
FYB1	FYN binding protein 1	Generation of second messenger molecules Generation of second messenger molecules Signal regulatory protein family interactions
FZR1	fizzy and cell division cycle 20 related 1	Autodegradation of Cdh1 by Cdh1:APC/C SCF-beta-TrCP mediated degradation of Emi1 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase Regulation of APC/C activators between G1/S and early anaphase Phosphorylation of Emi1 Senescence-Associated Secretory Phenotype (SASP) Assembly of the pre-replicative complex CDK-mediated phosphorylation and removal of Cdc6 Cyclin A/B1/B2 associated events during G2/M transition Cyclin A:Cdk2-associated events at S phase entry Transcriptional Regulation by VENTX Aberrant regulation of mitotic exit in cancer due to RB1 defects Antigen processing: Ubiquitination & Proteasome degradation
GADD45GIP1	GADD45G interacting protein 1	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
GAR1	GAR1 ribonucleoprotein	Telomere Extension By Telomerase rRNA modification in the nucleus and cytosol
GARNL3	GTPase activating Rap/RanGAP domain like 3
GBE1	1,4-alpha-glucan branching enzyme 1	Glycogen synthesis Glycogen storage disease type IV (GBE1)		Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GBF1	golgi brefeldin A resistant guanine nucleotide exchange factor 1	trans-Golgi Network Vesicle Budding VxPx cargo-targeting to cilium COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
GCAT	glycine C-acetyltransferase		Pyridoxal phosphate Glycine
GFPT2	glutamine--fructose-6-phosphate transaminase 2	Synthesis of UDP-N-acetyl-glucosamine
GFUS	GDP-L-fucose synthase	GDP-fucose biosynthesis	NADH
GGA1	golgi associated, gamma adaptin ear containing, ARF binding protein 1	TBC/RABGAPs Amyloid fiber formation
GGA3	golgi associated, gamma adaptin ear containing, ARF binding protein 3	TBC/RABGAPs MET receptor recycling Amyloid fiber formation
GIGYF2	GRB10 interacting GYF protein 2			Parkinson's disease (PD)
GLA	galactosidase alpha	Neutrophil degranulation Glycosphingolipid catabolism	Migalastat	Fabry disease
GLG1	golgi glycoprotein 1	Cell surface interactions at the vascular wall
GLIS3	GLIS family zinc finger 3			Permanent neonatal diabetes mellitus (PNDM)

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