|
|
NDUFA9 |
NADH:ubiquinone oxidoreductase subunit A9 |
- Respiratory electron transport
- Complex I biogenesis
|
- NADH
- Flavin adenine dinucleotide
|
|
|
|
NECAB2 |
N-terminal EF-hand calcium binding protein 2 |
|
|
|
|
|
NEFL |
neurofilament light chain |
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Ras activation upon Ca2+ influx through NMDA receptor
- RAF/MAP kinase cascade
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
|
|
- Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
|
|
|
NF2 |
NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor |
- Regulation of actin dynamics for phagocytic cup formation
- RHO GTPases activate PAKs
|
|
- Noonan syndrome and related disorders, including: Noonan syndrome (NS); Leopard syndrome (LS); Noonan syndrome-like with loose anagen hair (NS/LAH); CBL-mutation associated syndrome (CBL); Neurofibromatosis type 1 (NF1); Neurofibromatosis type 2 (NF2); Neurofibromatosis-Noonan syndrome (NFNS); Legius syndrome; Cardiofaciocutaneous syndrome (CFCS); Costello syndrome (CS)
- Malignant pleural mesothelioma
|
|
|
NINL |
ninein like |
- Regulation of PLK1 Activity at G2/M Transition
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Anchoring of the basal body to the plasma membrane
- AURKA Activation by TPX2
|
|
|
|
|
NKD2 |
NKD inhibitor of Wnt signaling pathway 2 |
|
|
|
|
|
NRBF2 |
nuclear receptor binding factor 2 |
|
|
|
|
|
PAEP |
progestagen associated endometrial protein |
|
- 12-Bromododecanoic Acid
- Palmitic Acid
- Glycerin
|
|
|
|
PATL1 |
PAT1 homolog 1, processing body mRNA decay factor |
- mRNA decay by 5' to 3' exoribonuclease
- mRNA decay by 5' to 3' exoribonuclease
|
|
|
|
|
PATZ1 |
POZ/BTB and AT hook containing zinc finger 1 |
|
|
|
|
|
PHLDB1 |
pleckstrin homology like domain family B member 1 |
|
|
|
|
|
PICK1 |
protein interacting with PRKCA 1 |
- Cell surface interactions at the vascular wall
- Trafficking of GluR2-containing AMPA receptors
|
|
|
|
|
PITX1 |
paired like homeodomain 1 |
|
|
- Congenital clubfoot; Congenital talipes equinovarus
|
|
|
PLK1 |
polo like kinase 1 |
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
- Polo-like kinase mediated events
- Golgi Cisternae Pericentriolar Stack Reorganization
- Golgi Cisternae Pericentriolar Stack Reorganization
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Phosphorylation of the APC/C
- Phosphorylation of Emi1
- Condensation of Prophase Chromosomes
- Separation of Sister Chromatids
- Resolution of Sister Chromatid Cohesion
- Regulation of PLK1 Activity at G2/M Transition
- Activation of NIMA Kinases NEK9, NEK6, NEK7
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Anchoring of the basal body to the plasma membrane
- RHO GTPases Activate Formins
- Mitotic Prometaphase
- Mitotic Metaphase/Anaphase Transition
- Mitotic Telophase/Cytokinesis
- Cyclin A/B1/B2 associated events during G2/M transition
- The role of GTSE1 in G2/M progression after G2 checkpoint
- AURKA Activation by TPX2
- EML4 and NUDC in mitotic spindle formation
- Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
|
- 3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol
- 3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide
- 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE
- 1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino]ethyl]-1,3-thiazol-2-yl]urea
- Wortmannin
- Fostamatinib
- Volasertib
|
|
|
|
PLK2 |
polo like kinase 2 |
- TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
- CD163 mediating an anti-inflammatory response
- NPAS4 regulates expression of target genes
|
|
|
|
|
POGZ |
pogo transposable element derived with ZNF domain |
|
|
|
|
|
POU6F2 |
POU class 6 homeobox 2 |
|
|
|
|
|
PPFIA2 |
PPFI scaffold protein A2 |
- Serotonin Neurotransmitter Release Cycle
- Norepinephrine Neurotransmitter Release Cycle
- Glutamate Neurotransmitter Release Cycle
- Dopamine Neurotransmitter Release Cycle
- Acetylcholine Neurotransmitter Release Cycle
- Receptor-type tyrosine-protein phosphatases
|
|
|
|
|
PPP1R18 |
protein phosphatase 1 regulatory subunit 18 |
|
|
|
|
|
PRMT6 |
protein arginine methyltransferase 6 |
- RMTs methylate histone arginines
- RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
|
|
|