UBC - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
FAF1	Fas associated factor 1
FAF2	Fas associated factor family member 2	Neutrophil degranulation RHOA GTPase cycle
FAM120B	family with sequence similarity 120 member B	PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
FAM162A	family with sequence similarity 162 member A
FAM168A	family with sequence similarity 168 member A
FAM3A	FAM3 metabolism regulating signaling molecule A
FAN1	FANCD2 and FANCI associated nuclease 1	Fanconi Anemia Pathway
FARP2	FERM, ARH/RhoGEF and pleckstrin domain protein 2	SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion RAC1 GTPase cycle
FAT1	FAT atypical cadherin 1
FBH1	F-box DNA helicase 1
FBXL15	F-box and leucine rich repeat protein 15	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
FBXO21	F-box protein 21	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
FBXO3	F-box protein 3
FBXO30	F-box protein 30	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
FBXO44	F-box protein 44	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
FCHO2	FCH and mu domain containing endocytic adaptor 2	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
FETUB	fetuin B
FGA	fibrinogen alpha chain	Platelet degranulation ER-Phagosome pathway Common Pathway of Fibrin Clot Formation MyD88:MAL(TIRAP) cascade initiated on plasma membrane Integrin cell surface interactions Integrin signaling GRB2:SOS provides linkage to MAPK signaling for Integrins p130Cas linkage to MAPK signaling for integrins Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) MyD88 deficiency (TLR2/4) IRAK4 deficiency (TLR2/4) MAP2K and MAPK activation Regulation of TLR by endogenous ligand Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF1 fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Post-translational protein phosphorylation Signaling downstream of RAS mutants Signaling by RAF1 mutants Amyloid fiber formation	Alteplase Reteplase Anistreplase Tenecteplase Sucralfate Zinc Alfimeprase Ancrod EP-2104R Lanoteplase Thrombin Prothrombin Human thrombin Thrombin alfa Anti-inhibitor coagulant complex Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Familial amyloidosis Inherited thrombophilia Afibrinogenemia; Dysfibrinogenemia
FIS1	fission, mitochondrial 1	Class I peroxisomal membrane protein import
FLOT1	flotillin 1	RIPK1-mediated regulated necrosis Regulation of necroptotic cell death Synaptic adhesion-like molecules RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle

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