Search Results for: SMAD3

280 interactions involving SMAD3 - SMAD family member 3 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
WWP1 WW domain containing E3 ubiquitin protein ligase 1
  • Downregulation of ERBB4 signaling
  • Stimuli-sensing channels
  • Regulation of RUNX2 expression and activity
  • Antigen processing: Ubiquitination & Proteasome degradation
WWP2 WW domain containing E3 ubiquitin protein ligase 2
  • Regulation of PTEN stability and activity
  • RHOQ GTPase cycle
  • RHOJ GTPase cycle
  • RHOU GTPase cycle
  • NOTCH3 Activation and Transmission of Signal to the Nucleus
XPO6 exportin 6
XRCC6 X-ray repair cross complementing 6
  • 2-LTR circle formation
  • Cytosolic sensors of pathogen-associated DNA
  • IRF3-mediated induction of type I IFN
  • Nonhomologous End-Joining (NHEJ)
  • Neutrophil degranulation
YBX1 Y-box binding protein 1
  • SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
  • mRNA Splicing - Major Pathway
  • mRNA Splicing - Minor Pathway
  • Processing of Capped Intron-Containing Pre-mRNA
  • Interferon gamma signaling
  • Noncanonical activation of NOTCH3
YY1 YY1 transcription factor
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • UCH proteinases
  • DNA Damage Recognition in GG-NER
  • TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
  • Estrogen-dependent gene expression
ZBTB16 zinc finger and BTB domain containing 16
  • Neddylation
  • Antigen processing: Ubiquitination & Proteasome degradation
  • Skeletal defects, genital hypoplasia, and mental retardation
  • Acute myeloid leukemia (AML)
ZBTB3 zinc finger and BTB domain containing 3
ZC3H12A zinc finger CCCH-type containing 12A
  • Regulation of CDH19 Expression and Function
ZCCHC14 zinc finger CCHC-type containing 14
ZDHHC4 zDHHC palmitoyltransferase 4
ZEB1 zinc finger E-box binding homeobox 1
  • Interleukin-4 and Interleukin-13 signaling
  • Negative Regulation of CDH1 Gene Transcription
  • Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
  • Fuchs corneal dystrophy (FECD); Fuchs endothelial corneal dystrophy
  • Posterior polymorphous corneal dystrophy (PPCD)
ZEB2 zinc finger E-box binding homeobox 2
  • Regulation of CDH11 gene transcription
  • Regulation of CDH11 gene transcription
  • Negative Regulation of CDH1 Gene Transcription
  • Positive Regulation of CDH1 Gene Transcription
  • Formation of the anterior neural plate
  • Formation of the posterior neural plate
  • Mowat-Wilson syndrome
ZFYVE9 zinc finger FYVE-type containing 9
ZMYM2 zinc finger MYM-type containing 2
  • Signaling by cytosolic FGFR1 fusion mutants
  • Signaling by FGFR1 in disease
  • Signaling by FLT3 fusion proteins
  • Signaling by FLT3 fusion proteins
  • Negative Regulation of CDH1 Gene Transcription
ZMYND11 zinc finger MYND-type containing 11
ZNF329 zinc finger protein 329
ZNF774 zinc finger protein 774
  • Generic Transcription Pathway
ZNF8 zinc finger protein 8
ZNF83 zinc finger protein 83

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