RBPMS - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
SNRPG	small nuclear ribonucleoprotein polypeptide G	SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs SARS-CoV-2 modulates host translation machinery
SNRPN	small nuclear ribonucleoprotein polypeptide N	mRNA Splicing - Major Pathway		Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
SNW1	SNW domain containing 1	Pre-NOTCH Transcription and Translation Pre-NOTCH Transcription and Translation Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells NOTCH1 Intracellular Domain Regulates Transcription NOTCH1 Intracellular Domain Regulates Transcription Downregulation of SMAD2/3:SMAD4 transcriptional activity Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Notch-HLH transcription pathway mRNA Splicing - Major Pathway RUNX3 regulates NOTCH signaling RUNX3 regulates NOTCH signaling NOTCH3 Intracellular Domain Regulates Transcription NOTCH3 Intracellular Domain Regulates Transcription NOTCH4 Intracellular Domain Regulates Transcription Formation of paraxial mesoderm
SPATA46	spermatogenesis associated 46
SPATA8	spermatogenesis associated 8
SPG7	SPG7 matrix AAA peptidase subunit, paraplegin	Processing of SMDT1 Mitochondrial protein degradation		Hereditary spastic paraplegia (SPG)
SPMIP6	sperm microtubule inner protein 6
SPMIP9	sperm microtubule inner protein 9
STRBP	spermatid perinuclear RNA binding protein
TBX6	T-box transcription factor 6	Formation of paraxial mesoderm Somitogenesis Formation of the posterior neural plate
TCEA2	transcription elongation factor A2
TCF7L2	transcription factor 7 like 2	Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Ca2+ pathway Binding of TCF/LEF:CTNNB1 to target gene promoters Repression of WNT target genes Repression of WNT target genes Signaling by TCF7L2 mutants Transcriptional Regulation by VENTX RUNX3 regulates WNT signaling Formation of definitive endoderm Regulation of MITF-M-dependent genes involved in cell cycle and proliferation Regulation of PD-L1(CD274) transcription		Type II diabetes mellitus
TEKT5	tektin 5
TENT2	terminal nucleotidyltransferase 2
TFG	trafficking from ER to golgi regulator	COPII-mediated vesicle transport Signaling by ALK fusions and activated point mutants		Thyroid cancer Non-small cell lung cancer
TIE1	tyrosine kinase with immunoglobulin like and EGF like domains 1		Fostamatinib
TINAGL1	tubulointerstitial nephritis antigen like 1
TLE5	TLE family member 5, transcriptional modulator	Repression of WNT target genes
TMEM277P	transmembrane protein 277, pseudogene
TMEM42	transmembrane protein 42

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