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SRPK2 |
SRSF protein kinase 2 |
- Maturation of nucleoprotein
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- Adenine
- Purvalanol
- Phosphoaminophosphonic Acid-Adenylate Ester
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SUMO2 |
small ubiquitin like modifier 2 |
- Vitamin D (calciferol) metabolism
- SUMO is conjugated to E1 (UBA2:SAE1)
- SUMO is transferred from E1 to E2 (UBE2I, UBC9)
- SUMO is proteolytically processed
- SUMOylation of DNA damage response and repair proteins
- SUMOylation of transcription factors
- SUMOylation of transcription cofactors
- SUMOylation of SUMOylation proteins
- SUMOylation of intracellular receptors
- SUMOylation of intracellular receptors
- SUMOylation of chromatin organization proteins
- SUMOylation of RNA binding proteins
- SUMOylation of DNA replication proteins
- Processing of DNA double-strand break ends
- Formation of Incision Complex in GG-NER
- Regulation of endogenous retroelements by KRAB-ZFP proteins
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TBC1D25 |
TBC1 domain family member 25 |
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TRIM25 |
tripartite motif containing 25 |
- ISG15 antiviral mechanism
- DDX58/IFIH1-mediated induction of interferon-alpha/beta
- Termination of translesion DNA synthesis
- Ovarian tumor domain proteases
- Interferon gamma signaling
- TRAF3-dependent IRF activation pathway
- TRAF6 mediated IRF7 activation
- TRAF6 mediated NF-kB activation
- TRAF6 mediated NF-kB activation
- NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
- Negative regulators of DDX58/IFIH1 signaling
- Negative regulators of DDX58/IFIH1 signaling
- SARS-CoV-1 activates/modulates innate immune responses
- SARS-CoV-2 activates/modulates innate and adaptive immune responses
- Evasion by RSV of host interferon responses
- RSV-host interactions
- PKR-mediated signaling
- Modulation of host responses by IFN-stimulated genes
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USP7 |
ubiquitin specific peptidase 7 |
- Ub-specific processing proteases
- Formation of TC-NER Pre-Incision Complex
- Transcription-Coupled Nucleotide Excision Repair (TC-NER)
- Dual incision in TC-NER
- Gap-filling DNA repair synthesis and ligation in TC-NER
- Regulation of TP53 Degradation
- Synthesis of active ubiquitin: roles of E1 and E2 enzymes
- Regulation of PTEN localization
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USP9X |
ubiquitin specific peptidase 9 X-linked |
- Downregulation of SMAD2/3:SMAD4 transcriptional activity
- Ub-specific processing proteases
- Synthesis of active ubiquitin: roles of E1 and E2 enzymes
- RHOU GTPase cycle
- RHOV GTPase cycle
- Peroxisomal protein import
- Peroxisomal protein import
- Amyloid fiber formation
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WBP4 |
WW domain binding protein 4 |
- mRNA Splicing - Major Pathway
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XPO1 |
exportin 1 |
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
- Rev-mediated nuclear export of HIV RNA
- NEP/NS2 Interacts with the Cellular Export Machinery
- Downregulation of TGF-beta receptor signaling
- Separation of Sister Chromatids
- Resolution of Sister Chromatid Cohesion
- Deactivation of the beta-catenin transactivating complex
- HuR (ELAVL1) binds and stabilizes mRNA
- RHO GTPases Activate Formins
- MAPK6/MAPK4 signaling
- Mitotic Prometaphase
- Cyclin A/B1/B2 associated events during G2/M transition
- Estrogen-dependent nuclear events downstream of ESR-membrane signaling
- EML4 and NUDC in mitotic spindle formation
- Heme signaling
- NPAS4 regulates expression of target genes
- Maturation of hRSV A proteins
- Transcriptional and post-translational regulation of MITF-M expression and activity
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YWHAQ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta |
- Activation of BAD and translocation to mitochondria
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- RHO GTPases activate PKNs
- TP53 Regulates Metabolic Genes
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
- Regulation of localization of FOXO transcription factors
- SARS-CoV-1 targets host intracellular signalling and regulatory pathways
- SARS-CoV-2 targets host intracellular signalling and regulatory pathways
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ZNF512B |
zinc finger protein 512B |
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