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PIBF1 |
progesterone immunomodulatory binding factor 1 |
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PLAGL1 |
PLAG1 like zinc finger 1 |
- TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
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- Transient neonatal diabetes mellitus (TNDM)
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PML |
PML nuclear body scaffold |
- SUMOylation of DNA damage response and repair proteins
- SUMOylation of ubiquitinylation proteins
- Regulation of TP53 Activity through Acetylation
- Interferon gamma signaling
- Regulation of RUNX1 Expression and Activity
- Regulation of PTEN localization
- HCMV Early Events
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- Acute myeloid leukemia (AML)
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PNMA1 |
PNMA family member 1 |
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PRMT1 |
protein arginine methyltransferase 1 |
- RMTs methylate histone arginines
- TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
- RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
- Extra-nuclear estrogen signaling
- Estrogen-dependent gene expression
- Maturation of nucleoprotein
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- S-adenosyl-L-homocysteine
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PTEN |
phosphatase and tensin homolog |
- Synthesis of PIPs at the plasma membrane
- Synthesis of IP3 and IP4 in the cytosol
- Negative regulation of the PI3K/AKT network
- Downstream TCR signaling
- TP53 Regulates Metabolic Genes
- PTEN Loss of Function in Cancer
- Ub-specific processing proteases
- Ovarian tumor domain proteases
- Regulation of PTEN mRNA translation
- Regulation of PTEN localization
- Regulation of PTEN stability and activity
- Transcriptional Regulation by MECP2
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- Vulvar cancer
- Breast cancer
- Malignant melanoma
- Prostate cancer
- Hepatocellular carcinoma
- Small cell lung cancer
- Endometrial Cancer
- Glioma
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RASSF1 |
Ras association domain family member 1 |
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- Nasopharyngeal cancer
- Non-small cell lung cancer
- Bladder cancer
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RASSF3 |
Ras association domain family member 3 |
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RIPK3 |
receptor interacting serine/threonine kinase 3 |
- TICAM1, RIP1-mediated IKK complex recruitment
- RIP-mediated NFkB activation via ZBP1
- TRIF-mediated programmed cell death
- TRP channels
- RIPK1-mediated regulated necrosis
- Regulation of necroptotic cell death
- TLR3-mediated TICAM1-dependent programmed cell death
- IKK complex recruitment mediated by RIP1
- Microbial modulation of RIPK1-mediated regulated necrosis
- SARS-CoV-1-mediated effects on programmed cell death
- SARS-CoV-1 activates/modulates innate immune responses
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RNF4 |
ring finger protein 4 |
- Processing of DNA double-strand break ends
- Antigen processing: Ubiquitination & Proteasome degradation
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RPL13 |
ribosomal protein L13 |
- L13a-mediated translational silencing of Ceruloplasmin expression
- Peptide chain elongation
- SRP-dependent cotranslational protein targeting to membrane
- SRP-dependent cotranslational protein targeting to membrane
- Viral mRNA Translation
- Selenocysteine synthesis
- Major pathway of rRNA processing in the nucleolus and cytosol
- Formation of a pool of free 40S subunits
- GTP hydrolysis and joining of the 60S ribosomal subunit
- Eukaryotic Translation Termination
- Regulation of expression of SLITs and ROBOs
- Response of EIF2AK4 (GCN2) to amino acid deficiency
- Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
- Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
- Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
- PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA
- ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
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SENP2 |
SUMO specific peptidase 2 |
- SUMO is proteolytically processed
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SERBP1 |
SERPINE1 mRNA binding protein 1 |
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SLC2A4 |
solute carrier family 2 member 4 |
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- Cellular hexose transport
- Transcriptional regulation of white adipocyte differentiation
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SLC9A1 |
solute carrier family 9 member A1 |
- Hyaluronan degradation
- Sodium/Proton exchangers
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- Amiloride
- Homoserine Lactone
- Cariporide
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SNW1 |
SNW domain containing 1 |
- Pre-NOTCH Transcription and Translation
- Pre-NOTCH Transcription and Translation
- Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
- NOTCH1 Intracellular Domain Regulates Transcription
- NOTCH1 Intracellular Domain Regulates Transcription
- Downregulation of SMAD2/3:SMAD4 transcriptional activity
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- Notch-HLH transcription pathway
- mRNA Splicing - Major Pathway
- RUNX3 regulates NOTCH signaling
- RUNX3 regulates NOTCH signaling
- NOTCH3 Intracellular Domain Regulates Transcription
- NOTCH3 Intracellular Domain Regulates Transcription
- NOTCH4 Intracellular Domain Regulates Transcription
- Formation of paraxial mesoderm
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SPN |
sialophorin |
- Cell surface interactions at the vascular wall
- Basigin interactions
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SPOP |
speckle type BTB/POZ protein |
- Hedgehog 'on' state
- SPOP-mediated proteasomal degradation of PD-L1(CD274)
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SQSTM1 |
sequestosome 1 |
- NRIF signals cell death from the nucleus
- p75NTR recruits signalling complexes
- NF-kB is activated and signals survival
- PINK1-PRKN Mediated Mitophagy
- Neddylation
- Interleukin-1 signaling
- Pexophagy
- Signaling by ALK fusions and activated point mutants
- KEAP1-NFE2L2 pathway
- Nuclear events mediated by NFE2L2
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- Paget's disease of bone and related disorders, including: ; Paget's disease of bone (PDB); Familial expansile osteolysis (FEO); Early-onset Paget's disease of bone (PDB2); Expansile skeletal hyperphosphatasia (ESH); Juvenile Paget's disease (JPD)
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SSX2IP |
SSX family member 2 interacting protein |
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